Nowadays, aging is the actual theme above the world. Scientists are working on to prevent aging. In this article, we discuss how Urolithin effects on human body and aging process.Urolithin A (UA) is a natural compound produced by gut bacteria from ingested ellagitannins (ETs) and ellagic acid (EA), complex polyphenols abundant in foods such as pomegranate, berries, and nuts.Mitochondria play a crucial role in cellular function and are particularly important in aging and decrepit cells by the function of mitophagy. During this process pathological mitochondria are killed, that controls the quality of mitochondrias and proteins.Mitochondrial dysfunction can trigger cellular responses associated with inflammation and cellular senescence.Urolithins (microbial metabolites) found in various tissues after ellagitannin consumption, has been demonstrated to possess antioxidant and anti-inflammatory effects.
Introduction: Phytoremediation is a natural process in which plants absorb and store heavy metals (Pb, Cd, As...) from the soil through their roots. An excess of metals can cause various diseases in the body.Contamination of soil with heavy metals may occur by oil and fuel spills from vehicles. There are several types of mass spectrometry that can be used to analyze contaminated soil, air, and water. The choice of technique depends on the specific application and the interesting analysis.Discussion: Proteogenomics studies often suffer from reduced sensitivity and specificity due to inflated database sizes. To control error rates, proteogenomics relies on a target-decoy search strategy.Conclusion: Determination of the chemical composition of heavy metals in soil, air and water (detection of pollution) is possible with mass spectrometry, more precisely with gas chromatography (GC-MS) and inductively coupled mass spectrometry (ICP-MS).
This thesis has studied the ethnocultural characteristics influence on business relationships. Quantitative research of Hofstede's study was carried out in Georgia. Based on the survey is revealed the Georgian society individual and cultural values that directly impact on business relationships. Our studies showed that the most pronounced cultural peculiarities of Georgia is a Power Distance indicator index (PDI). We have studied Hofstede's model according to the factors that determine the characteristics of the 5 criteria, and gave recommendations with regard to Georgia .
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