The discovery near Göktepe (Muğla province, Western Turkey) of an ancient quarrying site of white marbles and black stones has recently been reported by some authors. Assigning the provenance of stone from ancient artifacts to Göktepe is currently possible mainly thanks to chemical, EPR and MGS data. Petrographic description, which many researchers use to characterize ancient marbles, is still incomplete. Several thin sections of both types of stone were thus examined in this study, and also used for cathodoluminescence analysis. As the rock is more than 99% calcite, trace minerals could only be detected in some samples by XRD analysis of insoluble residues after acetic acid attack. Data on strontium and manganese contents and carbon and oxygen isotopes were also recorded, for better understanding of some petrographic features. A new method of grain size characterization was tentatively introduced to improve the description of grain size variability in the white marble. Microstructure and grain size measurements on thin sections of this marble identify two petrographic varieties: the first is extremely fine with signs of dynamic recrystallization, and the second exhibits texture and MGS similar to those of Carrara marble. Statuary samples of white marble from Villa Adriana (Tivoli, Rome), preliminarily assigned in a previous study partly to Carrara and partly to Göktepe quarry, are reconsidered here. A certain degree of variability was found in the structures and textures in the thin sections of the Göktepe black stone. It may have undergone transformations at an advanced stage of diagenesis. One important source of this variability seems to be a fluid alteration event, revealed by both isotopic and chemical data and trace mineral assemblages.

Traditionally, nicotine from second hand smoke (SHS), active or passive, has been considered the most prevalent substance of abuse used during pregnancy in industrialized countries. Exposure to environmental tobacco smoke (ETS) is associated with a variety of health effects, including lung cancer and cardiovascular diseases. Tobacco is also a major burden to people who do not smoke. As developing individuals, newborns and children are particularly vulnerable to the negative effects of SHS. In particular, prenatal ETS has adverse consequences during the entire childhood causing an increased risk of abortion, low birth weight, prematurity and/or nicotine withdrawal syndrome. Over the last years, a decreasing trend in smoking habits during pregnancy has occurred, along with the implementation of laws requiring smoke free public and working places. The decrease in the incidence of prenatal tobacco exposure has usually been assessed using maternal questionnaires. In order to diminish bias in self-reporting, objective biomarkers have been developed to evaluate this exposure. The measurement of nicotine and its main metabolite, cotinine, in non-conventional matrices such as cord blood, breast milk, hair or meconium can be used as a non-invasive measurement of prenatal SMS in newborns. The aim of this review is to highlight the prevalence of ETS (prenatal and postnatal) using biomarkers in non-conventional matrices before and after the implementation of smoke free policies and health effects related to this exposure during foetal and/or postnatal life.

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Quantitative cathodoluminescence (CL) has rarely been applied for the archaeometric studies concerning marble provenance, despite its potential. This paper develops the method and provides a new database of the parameters obtained from the main marble quarries used in antiquity. With a total number of 473 marble samples from ten districts of the central and eastern Mediterranean, it is the first database on quantitative CL, with the additional advantage of being the same samples that have already characterized by other conventional techniques and that are available in the literature. Focused on the measurements of the intensity peaks at the UV and visible spectra, registered by a spectrometer coupled to a scanning electron microscope (CL-SEM), the representative values are plotted on different useful diagrams to be applied in the identification of marble provenance studies, as a complementary tool of other analyses.