Fifty-three post-partum (p. p.) periods were studied in 38 mares. Uterine samples were taken on the 2nd and 5th days p.p. and thereafter every other day until ovulation. Uterine swabs were examined for bacteria and neutrophils and uterine biopsy specimens for neutrophils and lymphocytes. The occurrence of bacteria and leukocytes was most common on day 5 p. p. The dominant organism on day 2 was E . coli and on day 5 P-haemolytic streptococci. Thirty-four mares were inseminated during the first p. p. oestrus. Only the occurrence of neutrophils in day 5 biopsy specimens correlated with foal heat fertility. The pregnancy rate of mares with neutrophils or bacteria in uterine swabs was not significantly lower as compared to mares with no bacteria and no neutrophils. Routine swabbing of post-partum mares does not seem worthwhile.
Summary
Detomidine was administered twice to six foals (14 to 94 days old) using three different doses (10, 20 and 40 μg/kg bodyweight intravenously) in a double blind trial. Sedation, analgesia, heart rate and clinically observed side‐effects were recorded. Detomidine showed strong sedative effects at all doses tested. Sedation deepened very little by increasing the dose from 10 to 40 μg/kg bodyweight, but the duration of the effect was longer. Analgesia was considered good with the largest dose (40 μg/kg), and moderate or non‐existent with the lower doses. Detomidine caused a decrease in heart rate at all doses and other observed side‐effects included ataxia, heavy breathing, arrhythmia, sweating and frequent urination. No adverse effects were observed.
Summary
Fifty‐six post partum (p.p.) periods were studied in 41 mares. The mares were examined clinically (rectal palpation, ultrasound scanning, vaginoscopy) on the 2nd and 5th day p. p. and thereafter every other day until ovulation. Thirty‐five mares were inseminated in the first p. p. oestrus. The conception rate in the first oestrus was 45.7% and the final conception rate was 94.3 %. The mares were examined rectally, with an ultrasound scanner and vaginal speculum. None of the parameters examined (uterine size, tone and contents; endometrial folds; amount and character of vaginal contents; oedema and colour of portio vaginalis; age) was correlated with the fertility of foal heat insemination.
Zusammenfassung
Untersuchungen an der Stute post partum bezüglich der Fruchtbarkeit im Anschluß an die Fohlenrosse I. Rektale Palpation, Vaginoskopie und Ultraschalluntersuchung
Sechsundsiebzig post‐partum (p.p.)‐Perioden wurden bei 41 Stuten untersucht. Die Stuten wurden am 2. und 5. Tag p.p. sowie anschließend bis zur Ovulation jeden 2. Tag klinisch untersucht (rektale Palpation, Ultraschall‐Untersuchung, Vaginoskopie). Fünfunddreißig Stuten wurden während des ersten p.p.‐Östrus inseminiert. Die Konzeptionsrate beim ersten Östrus betrug 45,7%, die endgültige Konzeptionsrate dagegen 94,3%. Die Stuten wurden dabei rektal, mit dem Ultraschall‐Scanner und dem Scheiden‐Speculum untersucht. Keiner der untersuchten Parameter (Uterusgröße, Tonus und Inhalt des Uterus, Endometriumfalten, Menge und Art des Scheideninhalts, Ödematisierung und Farbe der portio vaginalis, Alter) war mit der Fruchtbarkeit im Anschluß an die Besamung während der Fohlenrosse korreliert.
Summary
Detomidine was administered throughout 10 pregnancies in eight mares. An intravenous injection of 20 pg/kg bodyweight was given weekly from Day 14 to Day 60 of gestation and thereafter every four weeks until parturition. One mare suffered torsion of the large colon and was destroyed on Day 86; the foetus was normally developed. A further mare aborted at 167 days. The remaining eight pregnancies continued to full term. One foal was delivered by caesarean section because of torticollis and, of the seven foals born spontaneously, one had bilateral upward patellar fixation at one month old. Therefore, although only six of the 10 foals developed normally, the other four cases showed no pathological similarities to suggest a common cause. Although these data were based on a small number of mares, they did not suggest that the repeated administration of detomidine had specific adverse effects on the pregnancies.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.