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Background: Type 2 diabetes mellitus (T2DM) is an emerging disease in the pediatric population. The association between T2DM and non-alcoholic fatty liver disease (NAFLD) has been described. Recent evidence suggests that sizes and composition of high-density lipoprotein (HDL) may be more important that HDL-C levels in predicting coronary heart disease. There is not data regarding the HDL subclasses distribution and composition in T2DM youths with NAFLD. Methods: This cross-sectional study included 47 adolescents with T2DM and 23 nondiabetic controls of both sexes aged 10 to 18 years. The presence of NAFLD was determined estimated proton density fat fraction (PDFF) by magnetic resonance by spectroscopy. We compared the HDL subclasses distribution (HDL2b, HDL2a, HDL3a HDL3b and HDL3c) and the HDL chemical composition (total protein, triglyceride, phospholipid, cholesteryl esters, and free cholesterol) between the groups of adolescents with T2DM and the control group. Results: Patients with T2DM and NAFLD had a significantly lower proportion HDL2b (P = .040) and a higher proportion of HDL3c (P = .035); higher proportion of TG

ResumenLa obesidad es un problema de salud mundial asociado con el desarrollo de enfermedades crónico degenerativas. La cirugía bariátrica es el tratamiento que ha mostrado mayor efectividad para la obesidad severa; el paciente debe modificar su estilo de vida para mantener la pérdida de peso a largo plazo. Se ha visto que las intervenciones cognitivo conductuales han sido efectivas para lograr este cambio en el paciente. El presente estudio busca evaluar la efectividad de una intervención cognitivo conductual grupal en la pérdida de peso y calidad de vida antes de la cirugía. Se incluyeron nueve pacientes con obesidad mórbida candidatos a cirugía bariátrica sin comorbilidades psiquiátricas. Se realizó una evaluación inicial de calidad de vida que medía peso e IMC [Índice de Masa Corporal, por sus siglas en español]. Los pacientes fueron sometidos a una intervención grupal con el objetivo de promover la pérdida de peso mediante técnicas cognitivo conductuales. El promedio de pérdida de peso fue de 5.7 kg en las cinco semanas que duró el tratamiento, mostrando significancia estadística de .001; a su vez, con la pérdida de peso disminuyó el IMC con una significancia estadística de .002. En cuanto a calidad de vida, hubo mejoría significativa en la percepción corporal y en la actitud al tratamiento. Palabras clave: psicología bariátrica, cirugía bariátrica, obesidad, calidad de vida, cognitivo-conductual. COGNITIVE BEHAVIORAL GROUP INTERVENTION FOR WEIGHT LOSS AND QUALITY OF LIFE IN PATIENTS CANDIDATES FOR BARIATRIC SURGERY AbstractObesity is a global health problem associated with the development of chronic degenerative diseases. Bariatric surgery has proven to be the most effective treatment for severe obesity. Despite surgery, patients must change their lifestyle in order to maintain weight loss in the long term. It has been reported that cognitive behavioral interventions have been effective to promote a lifestyle change and weight loss in obese patients. The aim of this study was to assess the effectiveness of a cognitive behavioral group intervention on weight loss and quality of life before surgery. Participants were nine morbidly obese patients, without psychiatric comorbidities, candidates for bariatric surgery. An initial assessment of quality of life that measured weight and BMI [Body Mass Index, for its English acronym] was performed. Patients underwent a group intervention in order to promote weight loss through cognitive behavioral techniques. The average weight loss was 5.7 kg during the five weeks of treatment, showing statistical significance of .001. In turn, along with weight loss, there was a decrease in BMI, with a statistical significance of .002. Regarding quality of life, there was significant improvement in body perception and attitude toward treatment.