This is a repository copy of Factors affecting local regrowth after watch and wait for patients with a clinical complete response following chemoradiotherapy in rectal cancer (InterCoRe consortium): an individual participant data meta-analysis.
Back lumbar hernia is a rare abdominal wall defect that usually presents spontaneously after trauma or lumbar surgery or, less frequently, during infancy (congenital). Few reports have been published in the literature describing primary lumbar hernia. A general surgeon will have the opportunity to repair only one or a few lumbar hernia cases in his/her lifetime. We report a case of a healthy 50-year-old man, with no previous surgeries or history of trauma, who presented to the outpatient department with abdominal discomfort, pain, and a sensation of a growing mass on his lower left back for 4 years. CT scan of the abdomen showed a mass in the left posterolateral abdominal wall. Specifically, a herniation of retroperitoneal fat between the erector spinae muscle group and internal oblique muscles through aponeurosis of the transversalis muscle (Grynfeltt hernia). The patient underwent a small lumbotomy, polypropylene mesh was placed and he recovered well. Although many techniques have been described for the surgical management of such hernias, none of them can be recommended as the preferred method. Our impression, however, is that the open approach, with a small lumbotomy, seems to be easy, safe and presents good postoperative recovery.
; Deborah Siqueira 6 RESUMO: Objetivo: Identificar os fatores prognósticos clínicos e anatomopatológicos nos portadores de tumor estromal gastrointestinal (GIST) gástrico submetidos à ressecção cirúrgica. Método: Estudo retrospectivo realizado no Instituto Nacional do Câncer (INCA), incluindo 29 casos de GIST gástrico c-Kit positivo submetidos à ressecção cirúrgica entre 1983 e 2004. Variáveis clínicas e anatomopatológicas foram investigadas quanto ao significado prognóstico, correlacionando-as com sobrevida global e sobrevida livre de doença. Resultados: O acompanhamento mediano foi de 35 meses. A sobrevida global, estimada em cinco anos, foi de 53%. As variáveis tamanho tumoral maior que 13,5 cm e presença de recidiva tiveram implicação prognóstica na sobrevida global conforme análise univariada (p=0,01 e p=0,03, respectivamente). A análise multivariada evidenciou que tamanho tumoral maior que 13,5 cm e presença de recidiva representaram fatores prognósticos independentes relacionados à sobrevida global (p=0,01 e p=0,03, respectivamente). As características tamanho tumoral maior que 13,5 cm e índice mitótico influenciaram significativamente (p=0,04 e p=0,04) a sobrevida livre de doença (análise univariada), porém apenas tamanho tumoral maior que 13,5 cm apresentou-se como fator prognóstico independente (p=0,04) relacionado à sobrevida livre de doença, quando utilizada a análise multivariada. Conclusão: O tamanho tumoral e a presença de recidiva representaram fatores prognósticos independentes relacionados à sobrevida global. Apenas o tamanho tumoral apresentou impacto adverso independente na sobrevida livre de doença (Rev. Col. Bras. Cir. 2006; 33(5): 298-304).
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