To assess whether routine measurement of serum calcitonin (CT) could improve the preoperative diagnosis of sporadic medullary thyroid carcinoma (MTC), 1385 consecutive patients presenting for nodular thyroid disease during the year 1991 were submitted to serum CT determination and fine needle aspiration cytology (FNAC). The clinical diagnosis was nontoxic nodular goiter in 1197 (86.4%) patients, toxic multinodular goiter in 65 (4.7%), autonomously functioning thyroid nodule (AFTN) in 64 (4.6%), and autoimmune thyroid disease (Graves' disease or Hashimoto's thyroiditis) with nodule(s) in 59 (4.3%). As controls, 177 patients with nonnodular thyroid disease and 32 normal subjects were also studied. Patients with FNAC suspicious of any kind of thyroid carcinoma and patients with elevated basal and pentagastrin-stimulated serum CT, regardless of the results of FNAC, were submitted to surgery. Eight (0.57%) patients (7 with nontoxic nodular goiter and 1 with AFTN) had elevated basal serum CT levels, ranging between 55-10,000 pg/mL. The pentagastrin test was abnormal in all of them. FNAC was suggestive of MTC in 2, thyroid carcinoma in 1, benign nodule in 3, and inadequate in 2. By histology, immunohistochemistry, and Northern blot analysis of total tumor RNAs, MTC was confirmed in all patients, including the 1 with AFTN, who had the association of microfollicular adenoma and a small MTC in the same lobe. After surgery, serum CT decreased to undetectable levels in 7 patients and remained undetectable in 6 of them during a mean follow-up of 22 months, although 1 of them had a positive response to pentagastrin. Forty-four patients in the group with normal serum CT levels had FNAC suspicious for differentiated thyroid carcinoma and were treated by surgery. Differentiated thyroid carcinoma, mostly papillary, was confirmed at histology in 43 subjects (3.1% of all thyroid nodules). In conclusion, the results of our study indicate that serum CT measurement is useful for the screening of sporadic MTC in patients with thyroid nodule(s). The prevalence of MTC, diagnosed by serum CT measurement in a 12-month period, among an unselected series of 1385 patients with nodular thyroid disease was surprisingly high: 0.57% of all thyroid nodules and 15.7% of all thyroid carcinomas. Serum CT measurement was superior to FNAC in suggesting the diagnosis of MTC and was devoid of falsely positive results. Increasing the diagnostic accuracy helped the surgeon to perform more radical treatment of MTC, thus achieving frequent normalization of postoperative serum CT levels. Whether this result indicates definitive cure remains to be established on the basis of longer follow-up.(ABSTRACT TRUNCATED AT 400 WORDS)

Spectral reflectance data originating from Unmanned Aerial Vehicle (UAV) imagery is a valuable tool to monitor plant nutrition, reduce nitrogen (N) application to real needs, thus producing both economic and environmental benefits. The objectives of the trial were i) to compare the spectral reflectance of 3 turfgrasses acquired via UAV and by a ground-based instrument; ii) to test the sensitivity of the 2 data acquisition sources in detecting induced variation in N levels. N application gradients from 0 to 250 kg ha-1 were created on 3 different turfgrass species: Cynodon dactylon x transvaalensis (Cdxt) ‘Patriot’, Zoysia matrella (Zm) ‘Zeon’ and Paspalum vaginatum (Pv) ‘Salam’. Proximity and remote-sensed reflectance measurements were acquired using a GreenSeeker handheld crop sensor and a UAV with onboard a multispectral sensor, to determine Normalized Difference Vegetation Index (NDVI). Proximity-sensed NDVI is highly correlated with data acquired from UAV with r values ranging from 0.83 (Zm) to 0.97 (Cdxt). Relating NDVI-UAV with clippings N, the highest r is for Cdxt (0.95). The most reactive species to N fertilization is Cdxt with a clippings N% ranging from 1.2% to 4.1%. UAV imagery can adequately assess the N status of turfgrasses and its spatial variability within a species, so for large areas, such as golf courses, sod farms or race courses, UAV acquired data can optimize turf management. For relatively small green areas, a hand-held crop sensor can be a less expensive and more practical option.

Intra-row weed control in organic or low-input cropping systems is more difficult than in conventional agriculture. The various mechanical and thermal devices available for intra-row weed control are reported in this review. Low-tech mechanical devices such as cultivators, finger-weeders, brush weeders, and torsion-weeders tend to be used in low density crops, while spring-tine harrows are mainly applied in narrow-row high-density crops. Flame weeding can be used for both narrow and wide-row sown crops, provided that the crop is heat-tolerant. Robotic weeders are the most recent addition to agricultural engineering, and only a few are available on the market. Nowadays, robotic weeders are not yet used in small and medium sized farms. In Europe, high-income niche crops are often cultivated in small farms and farmers cannot invest in high-tech solutions. Irrespectively of the choice of low- or high-tech machines, there are several weeders that can be used to reduce the use of herbicides, making of them a judicious use, or decide to avoid them

Autonomous mowers are battery-powered machines designed for lawn mowing that require very low human labour. Autonomous mowers can increase turf quality and reduce local noise and pollution compared with gasoline-powered rotary mowers. However, very little is known about the effects of autonomous mowing on encroaching weeds. The aim of this research was to compare the effects of an autonomous mower and an ordinary gasoline-powered mower on weed development in an artificially infested tall fescue (Festuca arundinacea Schreb.) turf with different nitrogen (N) rates. A three-way factor experimental design with three replications was adopted. Factor A consisted of three N rates (0, 75, and 150 kg ha −1 ), factor B consisted of two mowing systems (autonomous mower vs. walk-behind gasoline rotary mower equipped for mulching), and factor C which consisted of four different transplanted weed species: (a) Bellis perennis L., (b) Trifolium repens L.; (c) Trifolium subterraneum L.; and (d) Lotus corniculatus L. Of these, B. perennis is a rosette-type plant, while the other three species are creeping-type plants. The interaction between mowing system and transplanted weed species showed that the four transplanted weed species were larger when mowed by the autonomous mower than by the rotary mower. The autonomous mower yielded larger weeds probably because the constant mowing height caused the creeping weed species to grow sideways, since the turfgrass offered no competition for light. N fertilization increased turf quality and mowing quality, and also reduced spontaneous weed infestation. Autonomous mowing increased turf quality, mowing quality, but also the percentage of spontaneous weed cover.

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