We have been using sportomics to understand hypermetabolic stress. Cross Combat (CCombat) has recently been initiated as a high-intensity functional training method inspired by CrossFit. We used a CCombat session to induce metabolic stress and evaluated its effects on hydration and kidney function. Blood samples were collected from 16 elite-level professional male athletes engaged in training sessions over a 96-h protocol. Blood myoglobin increased by ~ 3.5-fold (119 ± 21 to 369 ± 62 nmol/L; p = .001) in response to the protocol, returning to the pre-exercise level within 48 h. Furthermore, d-dimer levels increased from 6.5 ± 0.6 to 79.4 ± 21.3 μmol/L (p < .001) in response to exercise decreasing during recovery with high variability among the studied athletes. Albuminemia and creatininemia increased ~ 10% and cystatin C increased ~ 240% (1.7 ± 0.1 to 5.7 ± 0.5 mg/L; p < .001; effect size = 2.4) in response to the protocol. We measured albuminuria (HuA) to assess kidney permeability to albumin caused by exercise. HuA increased ~ 16-fold (0.16 ± 0.03 to 2.47 ± 0.41 μmol/L; p < .001; effect size = 1.4) in response to exercise, dropping and reaching basal levels during 48 h. Here, we suggest that microalbuminuria can be used as an early, sensitive, easy, and inexpensive biomarker to evaluate hydration status changes during intensive exercise, decreasing chronic impairment in renal function.

The behavior of biochemical and immunological parameters investigated in the field conditions in athletes is important to influence in the management of recovery and disease prevention as well as, to support the training program, as well as to improve the physical conditioning associated with health and performance. However, for amputee athletes, Brazilian jiujitsu paradesport practitioners, there are no published data to date. Thus, the objective of this case study was to quantify the magnitude of biochemical, hematological, and urinary alterations after a simulated fight session in elite athlete with world titles. Outcomes were obtained through blood analysis of samples collected at four different moments (M1-fasting; M2-1.5 hr after caloric intake; M3-Immediately after the simulated fight; M4-24 hr after the simulated fight). Responses triggered by the simulated fight between baseline and after 24 hr were found to increase in monocyte (100%), neutrophil (20%), and insulin (57%) concentrations, while reductions were observed in eosinophils (−50%), lymphocytes (−26.6%), platelets (−22%), cortisol (−50%), and creatine phosphokinase (−45.2%). After 24 hr lactate values returned to baseline levels. The different changes in biochemical and hematological parameters observed constitute responses to acute physical exercise and were according to the level of the high performance athlete. From these data it will be possible to evaluate the periodization, training load, and recovery techniques according to the individual response verified. In addition, these data may be used for comparison purposes within this specific sport, whose literature is still limited.

No abstract

A privação do sono pode causar alterações metabólicas e cognitivas, afetando negativamente o indivíduo, seja no trabalho, na escola ou simplesmente no seu dia a dia. A literatura tem mostrado cada vez mais pessoas que optam pela troca de um boa noite de sono, seja por estudos, trabalhos ou simplesmente por estilo de vida. O objetivo do presente estudo foi, através de uma revisão narrativa da literatura a partir de artigos selecionados nas bases de dados PUBMED, SCIELO e BVS, através das palavras chave citadas abaixo, identificar os efeitos causados pela privação de sono nos aspectos cognitivos e metabólicos do indivíduo e o impacto causado no trabalho. Diante do exposto, foi possível observar que o sono tem papel fundamental no bem-estar e funcionamento do corpo de maneira geral. Sua privação pode gerar malefícios metabólicos e cognitivos, influenciando negativamente nos afazeres do dia a dia. Criar condições de se ter um boa noite de sono é essencial para a saúde do indivíduo, e sua produtividade. Mais estudos sobre o tema são necessários para uma maior conscientização das pessoas acerca da importância do sono.