The effect of laser exposure (the number of laser shots) on the stability of production of matrix (gentisic acid, sinapinic acid, nicotinic acid and benzoic acid) and biomolecule (insulin and cytochrome-c) ions is presented. Two methods of sample preparation, dried-droplet and pressure, were examined. In the case of pressure preparation, the dry powder sample was pressed mechanically with a pressure of 30 MPa. The best results were obtained for the pressure method and gentisic acid as matrix.
Despite the quick development of medicine and associated medical technology, there are still many patients with very severe neurological deficits who need far more sophisticated solutions, such as brain computer interfaces (BCIs). Our research aims at becoming familiar with BCI technology and the assessment of the possibilities of selected subjects in the area of P300-based BCI. An indirect aim is a discussion on the procedures of patient preparation for BCI installation, possible threats and limitations. Our research presents one of the possible efforts towards better documentation of investigating neural correlates of brain processing.
Steady State Visually Evoked Potentials have been known for several decades and they appear in the primary visual cortex of brain as a result of light stimulation of the sense of sight. In this article a simple method for electroencephalographic data acquisition is presented. The system is based on the DSM-51 unit connected to goggles with blinking diodes and Mindset-1000 EEG amplifier with 16 channels. We present self-developed hardware and method of effective synchronization for the light stimulation and brain activity recording.
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