BMPs and their receptors play an important role in the differentiation and development of ameloblastomas and AOTs, but may not explain the different biological behaviors of these lesions. The positive correlation observed in AOTs might be related to the formation of mineralized material in this tumor.
Con lito de interesses:Não Contribuição dos autores: VYNF concepção, planejamento e elaboração do manuscrito. TCL concepção, planejamento e elaboração do manuscrito. LPL orientação e planejamento do manuscrito. MABN planejamento e obtenção de dados importantes para elaboração do manuscrito. LBS orientação e obtenção de dados importantes para elaboração do manuscrito. PRFB orientação, planejamento e revisão.
Contato para correspondência:
AbstractIntroduction: Pemphigus vulgaris is an autoimmune disease characterized by ulcerative and bullous lesions on skin and mucous membranes. The aim of this paper is to report a case of oral pemphigus vulgaris, emphasizing the treatment and discuss some clinical and histopathologic features of this disease. Case Report: The patient is a 38-year-old male, feodermic, who was referred to a specialized service in oral diagnosis in the city of João Pessoa -Paraíba State, complains of multiple ulcerative lesions in the oral cavity, dysphagia, dysphonia, and marked weight loss. The diagnostic hypotheses were pemphigus vulgaris and mucous membrane pemphigoid. An incisional biopsy was performed on buccal mucosa and the diagnosis of the pemphigus vulgaris was made. Initially, the treatment of choice was systemic administration of prednisone 80 mg. In the first weeks, a remission of the oral lesions occurred. The dosage was gradually reduced to the current dose of 2.5 mg/day. Conclusion: Treatment was effective, once there was remission of all oral lesions.
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