Oral dirofi lariasis is very rare with non-specifi c clinical manifestations. Here, we report the case of a 65-year-old South American woman with a submucosal nodule on her right buccal mucosa. The nodule was slightly tender and painful. Differential diagnoses included mesenchymal (lipoma or fi brolipoma, solitary fi brous tumor, and neurofi broma) or glandular benign tumors (pleomorphic adenoma) with secondary infections. We performed excisional biopsy. A histopathological examination revealed a dense fi brous capsule and a single female fi larial worm showing double uterus appearance, neural plaque, well-developed musculature and intestinal apparatus. Dirofi lariasis was diagnosed, and the patient was followed-up for 12 months without recurrence.

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Con lito de interesses:Não Contribuição dos autores: VYNF concepção, planejamento e elaboração do manuscrito. TCL concepção, planejamento e elaboração do manuscrito. LPL orientação e planejamento do manuscrito. MABN planejamento e obtenção de dados importantes para elaboração do manuscrito. LBS orientação e obtenção de dados importantes para elaboração do manuscrito. PRFB orientação, planejamento e revisão. Contato para correspondência: AbstractIntroduction: Pemphigus vulgaris is an autoimmune disease characterized by ulcerative and bullous lesions on skin and mucous membranes. The aim of this paper is to report a case of oral pemphigus vulgaris, emphasizing the treatment and discuss some clinical and histopathologic features of this disease. Case Report: The patient is a 38-year-old male, feodermic, who was referred to a specialized service in oral diagnosis in the city of João Pessoa -Paraíba State, complains of multiple ulcerative lesions in the oral cavity, dysphagia, dysphonia, and marked weight loss. The diagnostic hypotheses were pemphigus vulgaris and mucous membrane pemphigoid. An incisional biopsy was performed on buccal mucosa and the diagnosis of the pemphigus vulgaris was made. Initially, the treatment of choice was systemic administration of prednisone 80 mg. In the first weeks, a remission of the oral lesions occurred. The dosage was gradually reduced to the current dose of 2.5 mg/day. Conclusion: Treatment was effective, once there was remission of all oral lesions.

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