Abstract:The authors present a clinicopathological case of Generalized Perforating Granuloma Annulare with extensive distribution of lesions, which are shown in various stages of development. Pustules, papular lesions in annular and arcuate distribution, erosions covered with hematic crusts, maculopapular atrophic areas and scars were the presentation forms of the disease. The histopathological aspects are discussed in detail within non-infectious granulomatous dermatitis. The text is based on the opinions of some authors in the literature. Furthermore, the therapeutic result obtained after three months of Dapsone at a dose of 100 mg per day was demonstrated by photographs. Keywords: Granuloma; Granuloma annulare; Dapsone Resumo: Os autores apresentam caso clínico-patológico de Granuloma Anular Perfurante Generalizado, com extensa distribuição de lesões, as quais se mostram em diversas fases de evolução. Pústulas, lesões papulosas, em distribuição anular e arciforme, erosões recobertas por crostas hemáticas, áreas máculo-atróficas e cicatrizes foram as faces de apresentação da doença. Os aspectos histopatopatológicos são detalhadamente discutidos, dentro das dermatites granulomatosas não infecciosas. O texto baseia-se nas opiniões de alguns autores da literatura. Além disso, o resultado terapêutico obtido foi demonstrado por fotografias, resultado de 3 meses de Dapsona na dose de 100 mg por dia.
INVESTIGATIONAbstract: BACKGROUND: Background: Actinic kera to sis is a fre quently-encoun te red pre ma lig nant lesion occur ring in areas expo sed to sun light in fair-skin ned elderly or mid dle-aged peo ple. Cryosurgery with liquid nitro gen is the most com mon method for trea ting the lesions. OBJECTIVES: The pri mary objec ti ve of this study was to mea su re the inten sity of pain during cryo sur gery by using the Visual Analog Scale (VAS). We also sought to iden tify the pain level dee med appro pria te by the patient, to assess the pro por tion of patients who con si de red it neces sary to redu ce the pain and, finally, to gauge whe ther or not addi tio nal anal ge sia was requi red. METHODS: Cross-sec tio nal study with patients refer red for cryo sur gi cal treat ment of acti nic kera to ses to the Sanitary Dermatology Outpatient Clinic. We applied a ques tion nai re to 112 patients [48 men (42.8%) and 64 women (57.2%)] after their treat ment for acti nic kera to ses, asking them to assess the inten sity of pain expe rien ced during sur gery and the pain that they con si de red to be bea ra ble or appro pria te for the pro ce du re. RESULTS: The mean refer red pain during sur gery was 32.85 mm on the Visual Analog Scale, while the mean pain dee med appro pria te by the patients was 23.01 mm. The dif fe ren ce bet ween the two means was sta tis ti cally sig ni fi cant (p <0.05). 30.4% of the patients repor ted in the direct and objec ti ve ques tion nai re that they nee ded the pain to be redu ced. CONCLUSIONS: Although the level of pain con si de red to be appro pria te by the patients was sta tis ti cally lower than the refer red pain, it did not reach the level at which it would be jud ged neces sary to pro vi de addi tio nal anal ge sia in this type of inter ven tion. Keywords: Actinic kera to sis; Cryosurgery; Pain mea su re ment Resumo: FUNDAMENTOS: a cera to se actí ni ca é lesão pré-malig na fre quen te, que ocor re em áreas expos tas à luz solar, em pes soas ido sas ou adul tas de meia-idade e pele clara. A crio ci rur gia com nitro gê nio líqui do é a moda li da de mais comum para o tra ta men to de cera to ses actí ni cas. Objetivos: o obje ti vo pri má rio deste estu do foi medir a inten si da de da dor duran te a crio ci rur gia, por meio da Escala Visual Análoga. Também bus cou-se iden ti fi car o nível de dor con side ra do ade qua do pelo pacien te, ava liar a pro por ção de pacien tes que con si de ram neces sá ria a dimi nui ção da dor senti da e veri fi car a neces si da de ou não de anal ge sia suple men tar. Métodos: Estudo trans ver sal com pacien tes enca mi nhados para tera pêu ti ca crio ci rúr gi ca de cera to ses actí ni cas no Ambulatório de Dermatologia Sanitária. Foram ava lia dos 112 pacien tes, após tra ta men to de cera to ses actí ni cas, apli can do-se um ques tio ná rio com per gun tas sobre a inten si dade da dor sen ti da duran te o pro ce di men to cirúr gi co, assim como a dor con si de ra da con for tá vel ou ade qua da ao proce di men to. Resultados: par ti c...
Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): CNPq, CAPES, FIPE-HCPA. Introduction The 12-lead electrocardiogram (ECG-12) is a useful tool in the assessment of athletes. The prevalence of normal electrocardiographic findings in elite Brazilian football players (EBFP) of different ethnicities is not well described. Purpose To compare the prevalence of normal ECG-12 findings in Caucasian, Mixed-race (MR), and Afro-Brazilian (AB) EBFP. Methods A multicenter cross-sectional descriptive study was conducted with exams performed on EBFP as a pre-participation assessment from February 18, 2002, through October 20, 2022. Results 4,363 EBFP from 51 professional clubs (from all five regions of Brazil; 15 states, and 21 cities), aged 15-35 years (median: 19 years; IQR: 16-23) were evaluated. 2,027 were Caucasians, 1,324 were MRs, and 1,012 were ABs. In general, we recorded 4,155 ECG-12 with normal variations (95.2%). Positive Sokolow-Lyon criteria for left ventricular hypertrophy was more prevalent in ABs (41.8%) than in Caucasians (33.4%), or MRs (32.7%). The prevalence of early repolarization in ABs (41.5%) was higher than in Caucasians (34.6%), or MRs (35.5%). The PR interval was longer in ABs (157.1 ms) than in Caucasians (151.4 ms), or MRs (153.3 ms), and the first-degree atrioventricular block was more frequent in ABs compared to MRs (4.2% vs. 2.3%, respectively). On the other hand, Caucasians had a higher prevalence of incomplete right bundle branch block (14.2%) than MRs (11.2%), or ABs (9.7%). In our sample, only three EBFP showed second-degree atrioventricular block Mobitz type I (0.07%; one Caucasian and two AB athletes). Conclusions This is the first large study to compare the prevalence of ECG-12 findings in EBFP from different ethnic groups. Those of AB origin have a significantly higher prevalence of ECG-12 findings compatible with the athlete's heart than Caucasians and MRs.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.