Background: Active management of third stage of labor is a feasible and inexpensive intervention that helps saving thousands of women's lives. Objective: The aim of the study was to compare the efficacy of IV ergometrine, rectal versus sublingual misoprostol in active management of third stage of labor. The same protocol was applied to
Background: Uterine leiomyomas are the most common gynecological benign myometrial neoplasms. They have been associated with infertility and recurrent abortion as well as obstructed labor and post-partum hemorrhage. They are the most important indication for hysterectomy. The renin angiotensin system (RAS), in particular angiotensin type 1 receptor (AT1R) and to a lesser extent angiotensin II, angiotensin converting enzyme (ACE) and angiotensin type 2 receptor (AT2R), are often upregulated during the progression from normal to malignant phenotypes indicating a possible correlation between RAS and tumor progression. The present study investigated the association of A1166C single nucleotide polymorphism (SNP) of AT1R gene and insertion deletion (I/D) polymorphism of ACE gene with uterine leiomyomas in Egyptian females.
Objective: The aim of this study was to measure serum zinc-α2-glycoprotein (ZAG) in pregnant Egyptian females with preeclampsia and eclampsia and to correlate its levels to biochemical measures of kidney function, lipid and glucose metabolism. Study Design: It was a retrospective study.
Patients and Methods:This study measured ZAG levels by enzyme linked immunosorbent assay (ELISA) in pregnant females with preeclampsia (PE) (no. = 40) and eclampsia (no.=20) and were compared to healthy gestational age-matched subjects (no.=20). In addition, the association of ZAG with kidney function, lipid and glucose metabolism was studied. Results: Significant difference was detected on comparing the different groups regarding ZAG levels (p = 0.001). Furthermore, ZAG was positively correlated to systolic blood pressure, urinary protein, fasting insulin and HOMA-IR. After adjusting for other parameters,the association between ZAG and SBP, urinary protein, serum insulin and HOMA-IR remained significant by multivariate linear regression analysis. Conclusion: The study noted that maternal ZAG serum levels are significantly increased in PE.
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