This analysis showed that neural lesions affecting the oral and maxillofacial region were rare and mostly benign in nature. Such lesions should be carefully diagnosed because of their association with life-threatening syndromes and the possibility of malignant transformation.

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Salivary gland tumors (SGTs) are relatively uncommon with considerable variations in demographic distribution. Epidemiological data in relation to SGTs in Saudi Arabia are limited.The aim of this study was to determine the relative frequency SGTs and to compare the data with studies from different parts of the globe.The records of the Histopathology Laboratory of College of Dentistry, King Saud University during the period from1985 to2011 were reviewed. Tumors were classified according to the 2005 WHO classification of SGTs.Patient's age, gender, and anatomical location of the tumors were recorded.SGTs were identified in 71(1.54%) out of 4,613 cases accessed during the period specified. Benign tumors were diagnosed in 39 cases (54.93%)and 32 (45.07%) were malignant. Pleomorphic adenoma was the most frequent benign tumor (42.25%) and mucoepidermoid (26.76%) was the most common malignant tumor. The palate (45.1%) was the most affected site by benign and malignant tumors followed by parotid gland (16.9%). Male to female ratio was 1.22:1. Benign SGTs peaked at the second decade of life and malignant tumors were more frequent in 5 th decade. Comparing with reports from other countries, findings indicate that SGTsto originate more in minor salivary glands with slight male predominance.

Differentiation between myofibroblasts and fibroblastic tumors as well as some malignancies can be challenging. Myofibroblastoma can behave as a malignant neoplasm, and the clinical distinction of this entity lies primarily in its recognition as a benign neoplasm.