No abstract

The possibility of platelet-rich plasma (PRP) on the improvement of bone and adjacent tissue recovery has previously been validated. However, there is insufficient data supporting the use of platelet-rich plasma to improve the healing of bone and adjacent tissues around an implant in the oral cavity. The purpose of this randomized controlled trial was to observe the effect of platelet-rich plasma (PRP) concentrate on marginal bone loss and bone density around immediate implant placement using Cone Beam Computerized Tomography (CBCT). This clinical study was conducted over a period of six months on 12 subjects, who were equally categorized into two groups. Group I was the control, whereas the subjects in Group II received PRP therapy at the surgical site. All subjects were given a standard treatment with a single implant system (DIO UFII hybrid sandblasted acid-etched implants). Inserted implants were analyzed through CBCT, and records were registered at baseline, at the 12th week before functional loading and the 26th week after functional loading. The bone loss was calculated at the proximal (mesial and distal) side of the implant and bone density at baseline, 12th week, and 26th week after implant placement. SPSS version 23.0 was used for statistical analysis of data. The changes in bone levels were measured and compared between the two groups using the Mann–Whitney U test, with no significant difference. Bone density was analyzed by an independent sample t -test, p value ≤ 0.05 was considered statistically significant. Again, no significant difference in bone density was observed between both groups at all three instances. Therefore, it can be concluded that local injection of PRP after immediate implant placement did not show any decrease in marginal bone loss or improvement in bone density. This trial is registered with NCT04650763.

Objective: The aim was to gain insight on patient factors and administrative shortcomings in the dental health department that prevent patients from seeking timely dental care. Study Design: Cross Sectional Survey. Setting: Punjab Dental Hospital, Lahore, Pakistan. Period: 7 January 2020 to 28 February 2020. Material & Methods: A structured close ended questionnaire was filled by information obtained from 400 patients that presented in the Exodontia OPD requiring extractions due to irreversible tooth damage. The data was collected from 244 (61%) females and 156 (39%) males. It was analyzed using SPSS version 20.0 and post stratification chi-square test was applied to see the significance of all comparative statistics. P value of <0.05 was taken as significant. Results: Out of 400 patients, 350 had not visited a dentist when the symptoms first appeared. Of these n=213 (60.86%) were females and n=137 (39.14%) were males. Majority of the patients were in the age range of 40-65 years and belonged to the low socioeconomic class n=213 (60.9%). The main causes of patients presenting now were pain and swelling. The major reasons reported for delayed visit were: “Self-medication” n=113 (24.57%),” Symptoms will resolve on their own” n=79 (17.17%),” No awareness” n=64 (13.91%),” Non serious and lazy attitude” n=39 (8.48%) and “Busy schedule” n=36 (7.83%). Conclusion: Our findings suggested that only a small proportion of people visited the dentist when the symptoms first appeared. Most of the patients ignored their symptoms to such an extent that the only possible treatment that could be offered was extraction of the concerned tooth. There was a general misconception that dental diseases are not very serious and can be resolved by over the counter medications. Thus, more dental awareness programs should be incorporated in the government health policy to increase focus on oral health.

Objective The carbon, titanium, and oxygen levels on titanium implant surfaces with or without ultraviolet (UV) pretreatment were evaluated at different wavelengths through X-ray photoelectron spectroscopy (XPS). Materials and Methods This interventional experimental study was conducted on nine Dio UFII implants with hybrid sandblasted and acid-etched (SLA) surface treatments, divided equally into three groups. Control group A samples were not given UV irradiation, while groups B and C samples were given UVA (382 nm, 25 mWcm2) and UVC (260 nm, 15 mWcm2) irradiation, respectively. The atomic ratio of carbon, titanium, and oxygen was compared through XPS. Results Mean carbon-to-titanium ratio and C1 peaks considerably increased in Group A compared to those in experimental Groups B and C. The intensity of Ti2p and O1s peaks was more pronounced for group C compared to that for groups A and B. Conclusions Although the decrease in surface hydrocarbons was the same in both UV-treated groups, the peak intensity of oxygen increased in the UVC-treated group. Thus, it can be concluded that compared with UVA irradiation, UVC irradiation has the potential to induce more hydrophilicity on SLA-coated implants.

Objectives This article identifies undiagnosed DM (UDM) cases in the Pakistani population by perceiving the signs and symptoms of DM and associating them with oral manifestations. Material and Methods In this cross-sectional study, patients showing at least three or more classical or warning signs like polydipsia, polyuria, polyphagia, and general weakness were considered UDM cases. Detailed oral examination for gingivitis, periodontitis, halitosis, xerostomia, and tongue manifestations was done followed by the hemoglobin A1c (HbA1c) analysis. Results Out of 5,878 patients, 214 UDM cases were identified, where 31.8% and 39.7% of the patients were diagnosed as prediabetics and diabetics, respectively, based on HbA1c analysis. Prevalence of gingivitis (97.6%), fissured tongue (91.8%), generalized periodontitis (85.9%), thick saliva (87.1%), xerostomia (84.7%), burning mouth syndrome (63.5%), yellow discoloration of tongue (57.6%), and ecchymosis/ulcers (43.5%) were more in diabetics as compared to prediabetic patients and normal population. Conclusion The oral manifestations can be crucial for identifying UDM cases. Dentists can play a pivotal role by taking detailed history and thorough oral examination. If three or more symptoms as concluded above are present, an HbA1c analysis should be conducted to prevent preop and postop complications associated with DM.