The risk of precipitating a convulsion in epileptic patients with methohexitone has been judged to vary widely. This article reports such complications arising during methohexitoneactivated E.E.G. recording in a series of 48 epileptic patients from whom anticonvulsant medication was 'i.£,ithheld. Two patients developed grand mal convulsions during induction with methohexitone 1· 0%. Two others exhibited status epilepticus of the petit mal type and one of the myoclonic type, after stopping an infusion of 0 ·09% methohexitone. The specijicity for methohexitone-induced convulsions in epileptics or crypto-epileptics is supported by a review of the literature.
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