Abstract-This paper presents a family variable step-size (VSS) affine projection (AP) adaptive filtering algorithms with good convergence speed and low steady state mean square error features. In the following, the family of VSS selective partial updates (SPU) affine projection algorithms are established which reduce the computational complexity. The stability bounds of the family of APA and SPU-APA algorithms are analyzed based on the energy conservation arguments. This analysis does not need to assume a Gaussian or white distribution for the regressors. We demonstrate the good performance of the proposed algorithms through simulations in system identification and acoustic echo cancellation scenarios.Index Terms-Adaptive filter, affine projection, selective partial update, variable step-size, stability analysis.
Background: Restricted intakes of saturated and trans-fatty acids and replacement with poly or monounsaturated fatty acids are emphasized in healthy diets. This study evaluates the effects of a six-month consumption of canola oil compared to sunflower oil on lipid profile and anthropometric parameters of people affected by dyslipidemia. Methods: This randomized controlled trial was conducted on 96 patients with dyslipidemia, who were randomly assigned into canola oil or the sunflower oil groups. The participants were instructed to record the contents of their daily meals, beverages, fruits, and snacks a day before treatment, at the second clinic visit, in the third month, and at the end of study (i.e., six months). Lipid profile and anthropometric parameters were compared between the two groups. Student t-test or Mann Whitney U test was used for statistical comparisons of variables between groups. Multivariate analysis was performed to adjust the confounding factor effects. Results: Of the enrolled participants, 44 (45.8%) were on sunflower oil diet and 52 (54.2%) on canola oil diet. We observed no change in anthropometric parameters and thus no significant difference between the two groups (p>0.05). Significant reductions in LDL-C (p<0.001), total cholesterol (p<0.001) and triglyceride levels (p<0.001), and significant elevation in HDL-C (p=0.008) were observed in canola oil group, as well as those who used sunflower oil. Conclusion: Dietary fats in the form of canola oil or sunflower oil effectively lower the serum cholesterol, LDL-C and triglyceride concentrations. They also result in an increase in serum concentration of HDL-C. These oils, however, did not modify general anthropometric parameters.
The paper considers the Popularity Adjusted Block model (PABM) introduced by Sengupta and Chen (Journal of the Royal Statistical Society Series B, 2018, 80, 365–386). We argue that the main appeal of the PABM is the flexibility of the spectral properties of the graph which makes the PABM an attractive choice for modelling networks that appear in biological sciences. We expand the theory of PABM to the case of an arbitrary number of communities which possibly grows with a number of nodes in the network and is not assumed to be known. We produce estimators of the probability matrix and of the community structure and, in addition, provide non‐asymptotic upper bounds for the estimation and the clustering errors. We use the Sparse Subspace Clustering (SSC) approach for partitioning the network into communities, the approach that, to the best of our knowledge, has not been used for the clustering network data. The theory is supplemented by a simulation study. In addition, we show advantages of the PABM for modelling a butterfly similarity network and a human brain functional network.
backgroundIn many countries, a young person who seeks medical care is not authorised to consent to their own assessment and treatment, yet the same child can be tried for a criminal offence.
Recently the role of indole and pyran rings in carcinogenesis has been well studied. Here we studied the effects and the possible mechanisms of the action of basal indole (I3A) and its novel indole derivative (C19H15F3N2O) on inhibition of proliferation cells in acute promyelocytic leukemia NB4 cell line by examining the expression of cell cycle genes. We treated NB4 cells with concentration of C19H15F3N2O for 24-72 h. The MTT and PI/Annexin V examinations were employed for assessment of the proliferation and apoptosis of NB4 cells. Both of Cyclin D and P21 were detected by the Real-time PCR. The western blotting analysis was also performed to show the protein levels for P21. A difference was regarded significant if p-value was less than 0.05. MTT assay showed that 15.12-1000 µg/mL C19H15F3N2O caused a time and concentration-dependent inhibition of NB4 cell proliferation. Exposure to higher concentrations of C19H15F3N2O resulted in significantly increased apoptosis rate in NB4 cells. RT PCR showed that C19H15F3N2O has up-regulated the expression of P21 and down-regulated the expression of Cyclin D. Western blotting experiments also demonstrated that the P21 expression in C19H15F3N2O treated cells has significantly increased, where compared with either untreated control cells or I3A treated cells. This newly (C19H15F3N2O) was able to inhibit NB4 cells proliferation and causes apoptosis of these cells more than I3A, and these effects are probably facilitated via cell cycle arrest. C19H15F3N2O might probably be introduced as a promising organic therapeutic reagent against APL.
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