Implication for health policy/practice/research/medical education Middle East pain syndrome is a novel disease, which requires more knowledge on its pathogenesis, prevention, and treatment. Possible cadmium contamination should also be considered. Notably, symptoms of this syndrome improved by fibromyalgia therapy consisting of muscle relaxants and vitamin D3 supplementation, and other related drugs. Therefore, we suggest more attention to this syndrome, in patients with various complaints as mentioned above.
The consequences of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection vary among persons, while some individuals are at high risk. Patients with systemic lupus erythematosus (SLE) and COVID-19 necessitate particular attention. SLE cases may be at particular risk for SARS-CoV-2 due to their dysregulated immune system and immunosuppressive treatments. Organ injury and administration of systemic glucocorticoids and other immunosuppressive agents are the risk factors for severe SARS-CoV-2. Additionally, SLE is not uncommon and could be severe in some ethnicities like African and Hispanic individuals and may be accompanied by poor outcomes of SARS-CoV-2. Thus, knowledge of the triggering immune response and therapeutic modalities in SLE and SARS-CoV-2 is necessary to guide treatment of this serious infectious disease in the background of SLE and vice versa.
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