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Punch grafting is more effective than follicular grafting in the treatment of stable vitiligo; however, follicular hair transplantation is cosmetically better, so we recommend it in exposed areas as face.

The management of posttraumatic scars is a great challenge. Autologous platelet‐rich plasma (APRP) and fractional carbon dioxide (CO2) laser can be applied as innovative treatments for posttraumatic scars. The aim of this study was to evaluate the efficacy, safety and complications of fractional CO2 laser exposure plus APRP injection in treating traumatic scars versus CO2 laser applied as a monotherapy. Twenty participants were treated 3 times at a 4‐week interval with a follow‐up visit. The scars were divided into an upper and lower half‐treated with fractional CO2 laser exposure plus APRP injection and CO2 laser alone, respectively. The scar was evaluated using the Vancouver scar scale (VSS), along with patient satisfaction. Twenty patients completed the 3 month treatment course. The mean VSS score improved significantly from 7.0 ± 3.97 to 3.25 ± 1.55 and 6.75 ± 1.77 to 3.85 ± 1.59 with fractional CO2 laser exposure plus APRP injection and CO2 laser exposure, respectively (p < .001). However, CO2 laser plus APRP was significantly superior to CO2 laser alone (p = .001), with fewer adverse effects. Our study shows that combined treatment with CO2 laser exposure plus APRP injection is safer and more effective for posttraumatic scar management than CO2 laser exposure alone.

Article informationBackground: Vitiligo is very common skin disease resulting from absence of active melanocytes and characterized by focal regions of depigmention, which may induce great psychological problems for the patients. Many therapies such as topical, systemic and phototherapy are not always successful, and re-pigmentation is often incomplete. Aim of the work:We aimed to compare between the efficacies of topical Khellin 4% and excimer light versus excimer light alone in treatment of vitiligo. Patients and methods:A comparative study that was carried out on 100 patients with 200 patches of vitiligo lesions, divided into group I; 100 patches treated with topical khellin 4% solution before excimer light, and group II; 100 patches treated with excimer light alone, for 30 minutes, two sessions per week for six months. Results:We found a significant difference decrease in surface area in group I when compared to the surface area in group II.The degree of improvement measured by quartile grading scale in the group I was higher than in group II. Moreover, the improvement rate in group I faster than group II. Topical khellin 4% solution and excimer light, were safe and well tolerated, however, mild erythema and burning sensation were observed and resolved after that. Conclusion:Topical khellin 4% solution and excimer light, are faster, effective, safe and well tolerated combination in treatment of vitiligo.

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