The aim of this paper is to present our results and experience in the treatment of snoring using the non-ablative Erbium: Yttrium Aluminum Garnet (Er:YAG) laser. Twenty-four patients (18 male and 6 female) with snoring problems due to soft palate hypertrophy were treated with 3 treatment procedures with Er:YAG 2940-nm laser (long pulse mode, 10 Hz, fluence 1.8-2.0 J/cm 2) performed at 2-week intervals. The treatment procedures were performed in outpatient settings. One treatment session lasts 15-20 min. Subjective (questionnaires) and objective (polygraph) outcome measures were assessed at baseline and 3 months after the final laser treatment. Wilcoxon Signed Rank was used to compare before and after scores. All polygraph variables showed some improvement 3 months after the end of treatment; however, only the reduction of the number of hypopnea episodes per hour was statistically significant (p = 0.034). In 13/24 patients, snoring time accounted for less than 5% of the sleep time after the treatment compared to 6/24 patients at baseline. The questionnaire survey showed statistically significant improvement in the quality of sleep and life of the patients as well as their partners after Er:YAG treatment (p < 0.001). The assessment of daytime sleepiness using the Epworth scale also improved 3 months after the end of treatment (p = 0.010). Based on our observations, the treatment of snoring with the Er:YAG laser is an effective and non-invasive therapeutic method. Further studies with long-term follow-up and a control group are warranted to confirm the promising results obtained in case series.

Background. Computational fluid dynamics (CFD), a rapidly developing instrument with a number of practical applications, allows calculation and visualization of the changing parameters of airflow in the upper respiratory tract.

Head and neck tumors can be very challenging to treat because of the risk of problems or complications after surgery. Therefore, prompt and accurate diagnosis is extremely important to drive appropriate treatment decisions, which may reduce the chance of recurrence. This paper presents the original research exploring the feasibility of Fourier transform infrared (FT-IR) and Raman spectroscopy (RS) methods to investigate biochemical alterations upon the development of the pleomorphic adenoma. Principal component analysis (PCA) was used for a detailed assessment of the observed changes and to determine the spectroscopic basis for salivary gland neoplastic pathogenesis. It is implied that within the healthy margin, as opposed to the tumoral tissue, there are parts that differ significantly in lipid content. This observation shed new light on the crucial role of lipids in tissue physiology and tumorigenesis. Thus, a novel approach that eliminates the influence of lipids on the elucidation of biochemical changes is proposed. The performed analysis suggests that the highly heterogeneous healthy margin contains more unsaturated triacylglycerols, while the tumoral section is rich in proteins. The difference in protein content was also observed for these two tissue types, i.e. the healthy tissue possesses more proteins in the anti-parallel β-sheet conformation, whereas the tumoral tissue is dominated by proteins rich in unordered random coils. Furthermore, the pathogenic tissue shows a higher content of carbohydrates and reveals noticeable differences in nucleic acid content. Finally, FT-IR and Raman spectroscopy methods were proposed as very promising methods in the discrimination of tumoral and healthy tissues of the salivary gland.

Penetrating neck traumas are traumas that pass through the platysma muscle, and they account for 5% to 10% of all neck traumas. Penetrating head traumas can damage vital structures such as the airways, esophagus, major nerves and vessels. Thus, patients with penetrating neck traumas should be treated in hospital, and doctors should be careful when deciding on the best treatment. Currently, the need for surgery can be established based on imaging tests, clinical status of the patient, medical history, physical examination, and laboratory tests. Exploratory surgery is not necessary particularly because it is associated with complications. We present two patients with penetrating neck traumas who were treated in our center: a 22-year-old patient with a foreign body that, for two years, mimicked a tumor, and a 45-year-old patient with a stab wound requiring immediate treatment. In the first patient, finding the foreign body earlier would have allowed an immediate removal, which would have prevented subsequent surgery and reduced the risks of leaving the foreign body in the neck. In the second patient, immediate contrast-enhanced computed tomography (CT) of the neck showed a foreign body, its size and position, which helped to plan surgery. Conclusions: In hemodynamically stable patients with penetrating neck traumas, doctors should choose the best treatment based on imaging, medical history, and physical examination.

Purpose. Bilateral vocal fold paralysis (BVFP) is a rare larynx disease manifested by dyspnea, which often requires surgical treatment. The aim of the study is to determine the effectiveness of unilateral arytenoidectomy with posterior cordectomy in the treatment of BVFP using the computational fluid dynamics (CFD) method. Methods. This study included 33 patients with BVFP who underwent unilateral laser arytenoidectomy with posterior cordectomy. Glottis area measurements and spirometry, as well as a self-assessment of respiratory efficiency were performed before the surgery and after the recovery period. Using the CFD method, computer models of the glottis were made. Then, changes in air pressure gradient and maximum air velocity at the level of glottis were calculated, and local fields of pressure and air velocities were obtained. Results. The values of glottal surface area (S), spirometry parameters (forced expiratory volume in one second (FEV1), forced vital capacity (FVC), and peak expiratory flow (PEF)), inlet air velocity at the glottal level as well as patients self-assessment of respiratory efficiency turned out to be significantly higher after the operation. The values of maximum velocity at the glottal level, pressure gradient at the glottal level turned out to be significantly lower after the surgery. We observed that the greater the increase in glottal surface area, the greater the decrease in self-assessment scales (visual analogue scale (VAS) and Medical Research Council (MRC)). Increased levels of spirometry parameters after the surgery correlated with smaller decrease of PEF-dependent pressure gradient at the glottal level (PEFΔPCFD). Conclusion. Unilateral laser arytenoidectomy with posterior cordectomy is an effective method for the treatment of BVFP. CFD is a useful tool to determine and visualize the effectiveness of surgical treatment in BVFP.

Computational Fluid Dynamics (CFD) is a fluid mechanics department that uses numerical methods to solve fluid flow issues. A review of the literature was done as well to summarize the usage of the CFD method in the assessment of airflow through the upper respiratory tract (GDO), especially in the larynx. CFD is now becoming a very useful tool not only for analyzing airflow patterns and mechanism of particle deposition in the larynx, but also for obtaining information on temperature, pressure and shear stress changes in GDO. It is a tool with which one can safely plan surgical treatment as well as predict its potential effects.

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Lasers have now become a common tool used in human lives. They have found their application in numerous, unrelated disciplines. Implemented commonly in medicine, in laryngological practice it has become a tool used primarily in endoscopic laryngeal microsurgery. The CO 2 laser is most commonly used in laryngeal microsurgery. In some cases the outcome of laser therapies is comparable to that achieved by means of traditional procedures-partial surgery through laryngofissure and radiotherapy. As a proved non-invasive method with a small number of complications, it has become elective surgery in stages T1 and T2 of laryngeal cancer. The benefits effecting from the use of a CO 2 laser also include shorter hospitalization, quicker recovery, lower costs and no need for a tracheotomy or feeding tube. Such a method is far better accepted by the patients, which contributes to an improved mental condition and healing. If unsuccessful, the therapy may be combined with radiotherapy or external access surgery with a well-preserved anatomy.