The aim of this study is to describe some characteristics of the sexual behavior of adolescents in Spain and to compare these characteristics according to gender, using a cross-sectional survey. Participants were 1.279 male and female adolescents who reported having had sexual intercourse. A questionnaire about sexual behavior was applied at their high schools and during school hours. Data were collected between 2006 and 2007. Mean age at the onset of sexual intercourse was 14.8 years in males and 15.0 years in females. Males and females were different according to the type of partner at the last sexual intercourse: 63.0% of males had a steady partner compared to 90.5% of females (p<0.01). The mean number of sexual partners during the last 12 months was higher in males than in females (M = 2.1 and M = 1.5 partners, for males and females, respectively, p<0.01). 50.0% of males had sexual intercourse under the effects of drugs versus 39.3% of females (p<0.01). STD and HIV prevention programs should be designed considering the differences according to adolescents’ sex.

The goal of this work is to determine whether relationship power in couples and sexual double standard can predict the risk of sexually transmitted infections/human immunodeficiency virus (STI/HIV) as a function of cultural and gender differences. The sample was made up of 689 adolescents living in Spain, of both sexes, aged between 14 and 19 years, who were sexually active in the past six months and who had a stable partner. Of them, 58.9% were native Spaniards and 41.1% were immigrants of Latin American origin. The results show that origin, age, double standard and the control over decision-making in the couple can predict the risk of STI/HIV; thus, the immigrants, the older participants, those who scored higher in double standard, and those with less control over decision-making were at higher risk of STI/HIV. With regard to gender, the males displayed more double standard and more control over decision-making, and the females displayed higher control over the relationship. The need to adapt STI/HIV prevention programs to the cultural and gender inequality differences in the couple is commented on in the discussion.

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Differences in HIV risk behaviours according to sociodemographic variables are shown. Therefore, taking into account sociodemographic factors in sexual education programs focused on adolescents seems to be necessary.

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The aim of this study was to describe some characteristics of vaginal, anal and oral sexual behavior in Spanish adolescents. It was a cross-sectional descriptive population study conducted using a probabilistic sample survey. The sample was composed of 4,612 male and female adolescents, of whom 1,686 reported having penetrative sexual experience. Sample size was established with a 97% confidence level and a 3% estimation error. Data collection took place in secondary education schools. Mean age of vaginal sex initiation was 15 years. Compared to females, males reported an earlier age of anal and oral sex initiation and a larger number of vaginal and anal sexual partners. Males also reported a higher frequency of penetrative sexual relations under the influence of alcohol or other drugs. A higher percentage of females than males reported not using a condom in their first anal sexual experience. This study provides a current overview of the sexual behavior of adolescents that can be useful for the design of future programs aimed at preventing HIV and sexually transmitted infections (STIs).

The goal of this study was to analyze how worry about sexually-transmitted infections (STI) and HIV influences attitudes and self-efficacy towards condom use, HIV-related knowledge, HIV-perceived susceptibility and HIV-misconceptions in a multicultural sample in Spain. The sample was composed of 3,051 adolescents aged between 14 and 19 years old who lived in Spain. Of these, 67.7% were native Spaniards and the remaining 32.3% were Latin American immigrants. Results showed that worry about STI and HIV has a direct influence on condom use self-efficacy and HIV-knowledge and HIV-perceived susceptibility. Native Spanish adolescents showed higher positive attitudes towards condom use, greater HIV-knowledge and HIV-perceived susceptibility, and lower negative attitudes towards condoms use and HIV-misconceptions than Latin American adolescents. In the discussion, the importance of worry about STI and HIV is highlighted as a mediator variable that can predict risky sexual behavior and is related to cultural origin.

Background Cutaneous lupus erythematosus is a chronic autoimmune disease that can leave important sequelae. Objective To determine the factors that predict the activity and damage of the skin disease, and the impact of tobacco on the efficacy of antimalarials using the Cutaneous Lupus Erythematosus Disease Area and Severity Index. Materials and Methods A consecutive case series was performed on 260 patients with cutaneous lupus erythematosus (α = 0.05; precision ± 6.5%). We carried out a descriptive analysis of the variables included, with a multivariate analysis to measure the association of variables with the Cutaneous Lupus Erythematosus Disease Area and Severity Index activity and damage ( p value < 0.05). Results The Cutaneous Lupus Erythematosus Disease Area and Severity Index activity was greater in smokers than non-smokers (4.0 ±5.3 vs 1.2 ±3.4, p = 0.006). No significant differences were observed in the Cutaneous Lupus Erythematosus Disease Area and Severity Index activity when the efficacy of antimalarials was analyzed between smokers and non-smokers. Cutaneous Lupus Erythematosus Disease Area and Severity Index damage was higher in smokers than in non-smokers (2.0 ± 3.6 vs 1.2 ± 2.6, p = 0.029). Cutaneous Lupus Erythematosus Disease Area and Severity Index activity was associated with: (a) being an active smoker (odds ratio 3.04, 95% confidence interval 1.68–5.51, p < 0.001; regression coefficient 2.05, 95% confidence interval 0.69–3.42, p = 0.003); (b) the chronic cutaneous lupus erythematosus subtype (odds ratio 1.98, 95% confidence interval 1.02–3.84, p = 0.044); and (c) C-reactive protein increase (≥0.5 mg/dL) (regression coefficient 2.56, 95% confidence interval 0.40–4.71, p = 0.020). Cutaneous Lupus Erythematosus Disease Area and Severity Index damage was associated with: (a) the activity (regression coefficient 0.11, 95% confidence interval 0.01–0.20, p = 0.024); (b) the chronic cutaneous lupus erythematosus subtype (regression coefficient 2.46, 95% confidence interval 1.37–3.56, p < 0.001); (c) the use of topical treatment (regression coefficient 1.31, 95% confidence interval 0.01–2.61, p = 0.049); and (d) systemic treatment (regression coefficient 1.44, 95% confidence interval 0.35–2.53, p < 0.010). Conclusion Smoking is related to an increase risk and a greater activity of cutaneous lupus erythematosus. The chronic cutaneous lupus erythematosus subtype and an increased C-reactive protein level were also associated with a higher disease activity. The sequelae were related to the activity, the chronic cutaneous lupus erythematosus subtype, and the use of topical and systemic treatment. The impact of tobacco on the efficacy of antimalarials may be caused by an increase in the severity of the disease more than by resistance in smokers.