An aberrant hemolysin produced by a Vibrio cholerae non-O1 strain NO37 (NO37-hly) was purified and characterized. NO37-Hly was antigenically very similar to El Tor hemolysin but differed in molecular weight (48,000 vs. 60,000), interaction with glucose, and hemolytic activity. Of 100 V. cholerae non-O1 strains other than the NO37 strain examined, none produced this aberrant hemolysin. The N-terminal amino acid sequence of NO37-hly was highly homologous to that of El Tor hemolysin.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.