Objective:The present study was undertaken to estimate and compare salivary interleukin-2 (IL-2) levels in patients with recurrent aphthous stomatitis, among healthy controls and their variation with age and sex.Study Design:Saliva was collected from 60 patients within the age range of 16-60 years which included 30 patients (17 Females and 13 Males) with recurrent aphthous stomatitis and healthy control group consisted of 30 participants (18 Females and 12 Males). IL-2 estimation was done in both the groups using enzyme linked immunosorbent assay (ELISA). Statistical analysis of the data was done using Independent ‘t’ test.Results:The results showed increased salivary IL-2 levels in patients with recurrent aphthous stomatitis compared to the healthy controls. The IL-2 levels were also increased in patients with the age group of 16-30 years compared to other age groups. Similar increase of IL-2 was also seen in female patients.Conclusion:Age related and sex related alterations of IL-2 in recurrent aphthous stomatitis patients were observed.
HSP70 is synthesized upon stress situations arising in cells of all living organisms. Expression of HSP70 indicates that stress plays an important role as a predisposing factor in oral submucous fibrosis and its subsequent progression to oral squamous cell carcinoma.
The authors discussed about various aspects of dental education in India, such as the admission procedure, the dental curriculum followed, clinical settings, classroom settings, faculty training in India, the attitudes and mindset of the dental students' and research in dental school setting. They have also discussed about the increasing number of the private dental colleges in the country, and the significant role of caste reservation in the admission process. Admission process is through common entrance exams (government or private) at state and national levels. The authors however recommended that separate exams for students interested in dentistry should be considered rather than common entrance exams for all health professions. Also, the Scoring system as practiced in United States for dental admission should be encouraged, rather than the ranking system followed here.
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