Background: Non-healing ulcers are a major health problem worldwide and have a great impact at personal, professional, and social levels. They are a major cause of non-traumatic lower limb amputations. The application of autologous Platelet Rich Plasma (PRP) has been a breakthrough in the treatment of non-healing ulcers, as it is an easy and cost-effective procedure, and provides the necessary growth factors that enhance tissue healing. The aim and objective of the study was to test the effectiveness of peri-ulcer autologous platelet-rich plasma injection in chronic non-healing ulcers and to assess the time taken for wound closure.Methods: This study was conducted on 50 patients during the period of November 2020 to October 2021 from the in-patients of the surgical unit in Dr. PSIMS and RF. Autologous PRP was prepared from whole blood utilizing a rapid, point-of-care system that works on the principle of density gradient centrifugation. Fifty (50) patients with non-healing ulcers of different etiologies, who met the inclusion criteria, were treated with peri-ulcer autologous PRP injections once weekly.Results: Of the 50 cases 29 were male and 21 were female, the mean age of the patients is 54.48±10.79 years. All the patients showed signs of wound healing with a reduction in wound size, and the mean time duration of ulcer healing was 6.75±1.47 weeks.Conclusions: This prospective study has demonstrated the potential safety and efficacy of autologous platelet-rich plasma injection for the treatment of chronic non-healing ulcers.
We all know that the paralysis condition is a loss of muscle function in the body parts. It can affect any part of your body at any time, then probably you may feel pain in the affected area. Technical and Therapeutic innovations are there to improve the quality of life Our goal is to develop a device that should be easy to use and should be affordable which consists of a basic health care monitoring system with nursing care. We know that these people can’t able to convey their messages or needs. To overcome this, we come up with a system that helps these patients to display messages in a very simple motion. This device can be designed to be mounted on the finger or to be inbuilt in their clothes.
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