Transforaminal lumbar interbody fusion (TLIF) is a relatively new technique of lumbar arthrodesis via posterior transforaminal approach to the disc, indicated mainly in cases of degenerative disc disease, low grade spondylolisthesis and reoperation for disc herniation, especially when there is indication for interbody fusion and posterior decompression. The aim of the study is to asses and evaluates the outcome of posterior instrumeneted transforaminal lumbar interbody fusion as a surgical treatment modality for symptomatic lumbar degenerative disease. this was a clinical trial study, including 20 cases of symptomatic degenerative lumbar disease who have failed medical treatment which includes one or more of the following: more than 40-year-old, having radiological evidence of lumbar degenerative disease whether stable or unstable. The duration of the study ranged from 6-12 months. Oswestry Disability Index (ODI) at baseline was ranged between 42 -80 with a mean value of 61.65±11.380 and it was decreased significantly after 1 year of surgery with a mean value of 35.35±11.417. VAS score at baseline was ranged between 4 -9 with a mean value of 6.80± 1.609 and it was decreased significantly after 1 year of surgery with a mean value of 0.75±0.910. TLIF is a technique which offers a simple, safe and effective treatment for degenerative lumbar spine disorders with great improvement of life quality of cases with surgery satisfaction.
A straightforward, sensitive, and quick spectrophotometric approach was created and validated for the detection of Ciprofloxacin hydrochloride, Moxifloxacin hydrochloride, and Roxithromycin hydrochloride in pure form. These techniques were based upon the fact that these antibiotics produced dark yellow ion pairs when combined with bromophenol blue. The binary complex in universal buffer solution of the optimum pH values was demonstrated at absorption maxima at 633 nm, 632 nm, and 633 nm for the three drugs, respectively, with bromophenol blue. Various parameters, such as the effect of time and the effect of reagent concentration, were optimized. Beer’s law plots were obeyed in the concentration ranges 2– 8 µg ml-1, 1– 4 µg ml-1, and 1– 6 µg ml-1, for the three drugs, respectively, with bromophenol blue. The detection limits were found to be 1.65, 0.83 and 0.79 μg mL-1, respectively, for Ciprofloxacin hydrochloride, Moxifloxacin hydrochloride, and Roxithromycin hydrochloride with bromophenol blue. The correlation coefficient value suggests that all three systems are linearly consistent.
This work aims to study the genetic characteristics of Staphylococcus aureus (S. aureus) strains isolated from 200 samples collected from humans (mouth, pharynx and hand) and food as poultry, milk and human food (cocked Liver and burgers sandwich). Genetic characteristics were evaluated epeningon resistance genes against some antibiotics that may be used for treatment of infected cases. A total of 23 isolates of S. aureus were identified from the collected 200 samples in an incidence rate of 11.5%. The identified strains were screened for resistance against 11 different antimicrobial agents. The strains showed a high level of resistance about (85-90%) to methicillin, penicillin; tobramycin, trimethoprim, sulfamethoxazone-trimethoprim and ciprofloxacin. Furthermore, moderate resistance to gentamycin, levofloxacin and lomfloxacin about (40-60%), while clindamycin and tetracycline antimicrobial agents were had a very low resistance, reaching (5-10%). The isolated S. aureus strains were monitored for the most important resistant genes the incidence rate of mecA, blaZ and tetK were (100%), while the aac(6'), aph(2") and norA were (45.5%) and (90.9%), respectively. This work revealed that about 70% of the isolated S.aureus strains were resistant to antibiotic drugs. Therefore, the miss, hub-hazard and uncontrolled use of antibiotics in veterinary medicine must be prevented.
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