A simple microbiological method to identify antimicrobial agents in urine is described. Of 1,514 consecutive urine specimens received from general practitioners, 302 (19.94%) contained antimicrobial activity. The antibacterial agent was identified confidently in 284 of these. Surprisingly, 83 (5.48%) urine specimens contained an antimicrobial substance not usually used in the treatment of urinary tract infection.
The question of measuring blood cholesterol values for assessing risk in individuals will continue to be debated. What is certain is that blood cholesterol concentrations in British men are high and constitute a considerable risk for ischaemic heart disease. The high risk approach in the United States and Great Britain would appear to have severe limitations. Given the present distribution of blood cholesterol concentrations in British men, nothing short of a population approach is likely to be effective, and even that would have to be applied from childhood if it is to have much effect.
SUMMARY The prevalence of antimicrobial substances in the urine of new patients attending a genitourinary department and patients reattending with a new condition (rebook patients) was 4a 1% (33 of 812 patients). Only 17 of 33 patients (52%) found to have an antimicrobial in the urine declared their antimicrobial intake at their initial physician interview and examination. The presence of antimicrobial substances had little influence on the diagnosis or management of patients.
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