Piperazine toxicity in a kitten

Veterinary pharmacovigilance. Part 2. Veterinary pharmacovigilance in practice – the operation of a spontaneous reporting scheme in a European Union country – the UK, and schemes in other countries

“…Other examples have included advice on the treatment of dogs with avermectin compounds, recall of a product containing an organophosphorus compound (diazinon) where mortalities had occurred in cats and dogs, and the morbidity arising in dogs and cats (see Tables 2 & 3) following vaccination (Gray, 1997b,c,d; Dean, 1998; Gray, 1998b). The potential toxicity of permethrin in the cat, and piperazine in kittens has also been publicized (Gray & Millar, 1987; Gray, 2000b). The recall of a sub‐potent batch of kennel cough vaccine (to protect against infection with Bordetella bronchiseptica in dogs) was publicized (by the company, after discussions with the VMD) in 1997 (Smitherman, 1997).…”