A case of paravenous retinochoroidal atrophy was followed over a period of more than 2 years. Rapid progression of the disease was reflected in the deterioration of visual acuity and fields. Electroretinographic recordings revealed reduced photopic and scotopic amplitudes according to the extent of the retinal lesions. In electrooculography virtually no slow and no fast light-induced oscillations could be recorded. These results suggest an involvement of the entire retinal pigment epithelium.
In a prospective study the effect of silicone oil injected in the vitreous cavity was monitored electrophysiologically in six patients who were treated for retinal detachment. Electroretinograms (ERG) and electrooculograms (EOG) were recorded before, shortly after, and up to four months following the removal of the oil. An evident increase of the standing potential could be observed in all eyes after removal of the silicone oil. In some patients the ERG amplitudes increased also. No fast oscillations and virtually no slow oscillations could be recorded in the EOG. Follow-up studies did not show a significant recovery of the bioelectric activity. Intravitreal silicone oil appears to cause an insulation effect which interferes with the propagation of electrical potentials. The result of the present study do not provide information concerning possible retinotoxic effects of silicone oil.
The purpose of this study was to compare the variability of the amplitude ratios and latencies of the electro-oculogram (EOG) light peak (LP) in three different recording conditions: Arden ratio (dark trough (DT): 12 min), modified Arden ratio (DT: 15 min) and light peak/dark baseline ratio (LP/BL: 35 min of dark adaptation). Additionally, EOGs from eyes with dilated and undilated pupils were recorded. The light intensity stimulating the eyes with dilated pupils was attenuated 1 log unit. The EOG amplitude ratios displayed no significant difference between the three conditions tested. The comparison of implicit times (time from onset of light exposure to LP) revealed significantly (p < 0.001) shorter values when the recording of the LP was preceded by a dark adaptation of 35 min. The broadening of the curves in DT/LP recordings might be caused by a superposition of a residual dark oscillation on the LP. The recordings from eyes with dilated pupils – stimulated with 1 log unit lower intensity – revealed lower amplitude ratios than the recordings from eyes with undilated pupils.
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