Introduction:Dyslipidemia and hyperglycemia are metabolic abnormalities commonly found in young patients with Type 1 diabetes mellitus (T1DM) and both increase the risk of cardiovascular disease.Methods:This cross-sectional study was aimed to evaluate the pattern of dyslipidemia and its relationship with other risk factors in children and adolescents with T1DM. A total of 576 T1DM patients aged 10–18 years who attended Changing Diabetes in Children, a pediatric diabetes clinic in Bangladesh Institute of Research and Rehabilitation for Diabetes, Endocrine and Metabolic Disorders over 1 year period from July 2015 to June 2016 were included in this study.Results:The overall frequency of dyslipidemia was 65%. The high triglyceride, high cholesterol, high low-density lipoprotein (LDL) and low high-density lipoprotein were found in 50%, 66%, 75%, and 48%, respectively. Compared to patients without dyslipidemia, patients with dyslipidemia had significantly lower mean body mass index (kg/m2) (18.4 [interquartile range; 16.2–21.4] vs. 19.5 [17.3–21.5] (P = 0.005)); significantly higher median fasting blood sugar (12.7 [9.9–15.2] vs. 10.6 [7.9–12.6] (P < 0.0001)) and higher median glycosylated hemoglobin (9.8 [8.4–11.8] vs. 7.9 [9.3–10.5] (P < 0.0001)). Hypertension was significantly higher in dyslipidemic patients (9.4% vs. 2.5% P < 0.002).Conclusion:More than half (65%) of our children and adolescents with T1DM had dyslipidemia, among them high LDL was the most common. These findings emphasize the screening of lipid profile in T1DM children and adolescents.
The purpose of the cross sectional descriptive type of study was to document the childhood immunization coverage and its association with parental socio-demographic characteristics. For this, 160 parents of 160 children from a selected rural area of Chittagong, Bangladesh were selected by purposive sampling technique and data were collected by face to face interview using a semi-structured questionnaire. Immunization coverage of the children was about 82%. Parental age, gender and their decision (governmental or private service from where immunization done) were significantly associated with the children immunization coverage (p < 0.01, p < 0.01 and p < 0.05, respectively). The result may be helpful to policymakers for future planning and implementation of children immunization programme to improve children immunization coverage in Bangladesh.Mediscope Vol. 4, No. 1: Jan 2017, Page 25-29
The study, a cross-sectional survey, was carried out at the Department of Biochemistry in Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) General Hospital from July 2015 to June 2016. A total of 576 clinically diagnosed children and adolescents with type 1 diabetes mellitus (T1DM) aged 10-18 years attending in ‘Changing Diabetes in Children’ clinic, BIRDEM-2, Dhaka were selected according to appropriate inclusion and exclusion criteria. The study subjects underwent detailed medical history and examination. Fasting blood samples were drawn from the participants for biochemical assays such as fasting blood sugar (FBS), glycated haemoglobin (HbA1c), total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides. Anthropometric data and blood pressures both systolic and diastolic were measured. Student unpaired t-test and Chi-square test were used to determine the association between different groups. Out of 576 T1DM patients, 45.0% (259) were male and 55.0% (317) were female. Of the 576 T1DM patients, 35.1% were without dyslipidemia (DLP) and 64.9% were with DLP. Study revealed that the patients with DLP were more likely to have higher values of HbA1c (10.1±2.2% vs 9.4±1.9%, p < 0.001) and FBS (13.0±4.4 mmol/L vs 10.2±2.9 mmol/L, p < 0.001). A substantial proportion of children and adolescents with T1DM had DLP. We found an association between poor glycemic control and abnormal lipid profiles in those patients. Mediscope Vol. 5, No. 1: Jan 2018, Page 15-21
Tetanus Toxoid (TT) is a routine vaccination activity under Expanded Program on Immunization (EPI) in Bangladesh. This was a descriptive type of cross-sectional study with a sample size of 110, selected purposively by non-probability sampling technique. Data were collected through a pretested questionnaire. The aim of this study was to assess TT vaccination coverage among the women of child bearing age, Rangamati Pourashava. As per survey, among 110 respondents, 29 (26.4%) were of 15-25 years, 52 (47.3%) were of 26-35 years, 25(22.7%) were of 36-45 years & only 4(3.6%) were of >45years. In this study, the major group, 86(78.2%) were married, 17(15.4%) were unmarried & only 7 (6.4%) were widow. Most of the respondents considered vaccination as the way of disease prevention, so that the coverage being 92 (83.6%) in case of TT vaccination. It was found that 70% women received TT vaccine from Government EPI centers followed by 23.6% from NGO facilities and only6.4% from private clinics. Among the respondents, 56.3% respondents had completed their dose schedule of TT vaccine respectively. Most of the respondents had their vaccination card. The percentage was 70 for TT respectively. Among others, 20% failed to follow it because of forgetfulness of doses and 3.34% because of losing their card. So, TT vaccination coverage among the women of child bearing age was satisfactory but it also suggests that more awareness campaign for vaccination is sensational among the mass people of our country. This study TT vaccination status among women of child bearing age will help to get idea about the woman of our country regarding the situation. Mediscope Vol. 8, No. 1: January 2021, Page 40-44
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