Lymphoepithelial carcinoma of the salivary glands is a rare neoplasm that is characterized by a non-neoplastic lymphocytic infiltration associated with an epithelial proliferation. It involves mainly the parotid gland. Racial and geographical factors contribute to the pathogenesis of this tumor. We report a case of a 70-year old woman from a non-endemic area who presented with several months history of swelling in the parotid region. Magnetic resonance imaging showed a parotid mass suggestive of a pleomorphic adenoma. The diagnosis of lymphoepithelial carcinoma of the parotid gland was performed on the surgical specimen. A primitive nasopharyngeal carcinoma was ruled out by random biopsies of the nasopharynx mucosa. The Epstein-Barr virus (EBV) was absent in neoplastic cells. We insist that, even in non-endemic areas and when clinical and radiological characteristics are not suggestive of malignancy, intra-operative frozen section analysis should be used in order to ensure the appropriate treatment.
Background: Dentigerous cysts are seen as benign pathology associated with developing, unerupted teeth. Individuals affected present with slow growing expansion of the bone, straw-coloured fluid on aspiration and displacement of involved and adjacent teeth. Case Report: An 11-year-old boy was referred with a painless reddish mass of three months duration. Examination revealed mild, diffuse swelling over the left maxillary region with an erythematous, soft tissue sessile swelling intraorally. Orthopantomograph showed radiopacity over the left maxillary sinus with displaced 27, 28 crowns. Contrast computed tomography (CT) and angiography identified feeder vessels from the branches of the left internal maxillary artery. Treatment and Follow-up: Embolisation was performed initially to block the supplying artery. Enucleation of the lesion followed three days post-embolisation. A histopathological examination of the lesion was carried out once enucleation complete. A review and monitoring programme was followed at three-, six-and ninemonth intervals. Conclusion: Judicial use of contrast CT and angiography can aid accurate diagnosis of erythematous oral growths in young patients.
This clinical report describes the oral rehabilitation of a 22‐year‐old‐man diagnosed with a variant of hypoplastic amelogenesis imperfecta. The treatment approach was multi‐disciplinary, and it included the surgical procedure of Lefort I osteotomy, surgical crown lengthening, and metal‐ceramic‐fixed dental prostheses. The patient was satisfied with the esthetic and functional outcome.
Résumé -Introduction : le kératokyste odontogéne (KKO) est une des tumeurs odontogènes les plus fréquentes. Plusieurs travaux se sont intéressés à l'étude de cette lésion depuis sa première description afin de pouvoir comprendre son comportement biologique. Matériel et méthode : il s'agit d'une étude rétrospective immunohistochimique des marqueurs PCNA, Ki67 et P53 chez 40 patients opérés pour un KKO. Résultats : ces marqueurs sont retrouvés dans les couches suprabasales de l'épithélium de la paroi kystique. Il n'y a pas de différence statistiquement significative dans l'expression de ces marqueurs entre les différentes formes cliniques (sporadique, récurrent et syndromique), et il n'existe pas de corrélation entre ces marqueurs et la survenue d'une récidive. Conclusion : PCNA, Ki67 et P53 ne sont pas des marqueurs pour l'histopronostic des KKO.Abstract -Immunohistochemical study of proliferative (Ki67, PCNA) and apoptotic (P53) factors of 40 cases of odontogenic keratocysts. Introduction: the odontogenic keratocyst (OKC) is one of the most prevalent odontogenic tumours. Since its initial description, a number of studies have focused on different aspects of this lesion, attempting to explain its distinctive biological behavior. Patients and methods: a retrospective immunohistochemical studies of the expression of PCNA, Ki67 and p53 protein in 40 patients treated for OKC. Results: in the OKCs, the positivity of these markers was expressed mostly in the suprabasal layers of cystic epithelium. There is no statistically significant difference of expression between the different clinical forms (sporadic, recurrent and syndromic OKC), neither a correlation between the expression of this markers and recurrence. Conclusion: PCNA, P53 and Ki67 can not be considered as prognostic factors of OKC.
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