Fibrous dysplasia in the maxillomandibular region: retrospective study

Abstract

Background: Dentigerous cysts are seen as benign pathology associated with developing, unerupted teeth. Individuals affected present with slow growing expansion of the bone, straw-coloured fluid on aspiration and displacement of involved and adjacent teeth. Case Report: An 11-year-old boy was referred with a painless reddish mass of three months duration. Examination revealed mild, diffuse swelling over the left maxillary region with an erythematous, soft tissue sessile swelling intraorally. Orthopantomograph showed radiopacity over the left maxillary sinus with displaced 27, 28 crowns. Contrast computed tomography (CT) and angiography identified feeder vessels from the branches of the left internal maxillary artery. Treatment and Follow-up: Embolisation was performed initially to block the supplying artery. Enucleation of the lesion followed three days post-embolisation. A histopathological examination of the lesion was carried out once enucleation complete. A review and monitoring programme was followed at three-, six-and ninemonth intervals. Conclusion: Judicial use of contrast CT and angiography can aid accurate diagnosis of erythematous oral growths in young patients.

Spectrum of fibro osseous lesions of jaw: An institutional study

“…A relatively constant ratio of fibrous tissue to bone throughout a given lesion is characteristic. 18 The fibroblasts exhibit uniform spindleshaped nuclei. The bony trabeculae assume irregular shapes likened to Chinese characters, without any functional orientation.…”

Craniofacial Fibrous Dysplasia of the Mandible: A Case Report and Literature Review

“…Genetically it is expressed in two ways, monostotic (56-70%) or polyostotic (30-47%) [5,7,[21][22][23]. The most frequent location for FD in descending order is the maxilla, mandibule and frontal bones [7,18].…”

“…The first line of treatment is surgical, which can be conservative or invasive, through resection and subsequent reconstruction [5,21,29,30]. It has also been determined that observation and constant monitoring is feasible in incidentally found lesions, without signs or symptoms associated.…”

“…It has also been determined that observation and constant monitoring is feasible in incidentally found lesions, without signs or symptoms associated. Recurrence of FD is common, reaching up to 50% in children until the end of growth, and is the most common cause for reoperation [6,21].…”

“…On the other hand, it has been shown that therapy with intravenous bisphosphonates (Zoledronic acid or Pamidronate) and Denosumab (RANKL monoclonal antibody) have been effective in relieving pain and normalizing bone turnover. There are some studies that report the complete or partial disappearance of lesions after prolonged therapy with bisphosphonates [31,32], however, its use is recommended in the symptomatic polyostotic variable [21,31,33].…”