After extensive counseling the parents opted for termination of the pregnancy. Post mortem examination confirmed the diagnosis. The diagnosis of diaphragmatic hernia is rarely made in the first trimester. Ultrasound diagnosis of the severest cases of congenital diaphragmatic hernia with early herniation of the viscera in the thorax is possible in the first trimester if fetal anatomy is routinely examined in a systematic way. Hallmarks of the diagnosis in the first trimester as well as in later pregnancy are the presence of the stomach, bowel or liver in the chest, the shift of the mediastinum and the displacement of the heart.
P02.44Congenital diaphragmatic hernia in a Saudi population: a 5-year review S. Sultan, H. A. Wahbi
King Abdulaziz Medical City, Saudi ArabiaObjectives: To study the incidence, the ultrasound findings, the associated anomalies and the outcome of congenital diaphragmatic hernia (CDH) in a Saudi population covered by the National Guard Hospital. Methods: A retrospective chart review of the antenatal records of all patients who were diagnosed as carrying a fetus with CDH from January 2000 to December 2005 was performed. Maternal demographic features, the ultrasound findings and the associated abnormalities and their frequencies, and the pregnancy outcome were reported. The incident was calculated per 10 000 births. Results: Thirty-two patients were identified. The incidence of CDH was 10 per 10 000 births, the stillbirth rate was 10%, early neonatal death was 17% and survival to surgery (7-10days) was 70%. CDH was in the left side of the chest in 80% of cases, in the right side in 13% and was bilateral in 7% of the cases. Liver was found in the chest in 10% of the fetuses. Associated cardiac anomalies were found in 34%, central nervous system (CNS) anomalies in 14% and chromosomal abnormalities in 10% of the cases. No patient had termination of pregnancy. Second-trimester miscarriage was reported in 1 patient.
Conclusion:The incidence of CDH in this Saudi population is among the highest in the world this might be due to high incidence of intermarriages. CDH is associated with a favorable neonatal outcome to surgery, this might be due to the low incidence of chromosomal and CNS anomalies in this cohort and the association of correctable congenital heart anomalies.
P02.45Our experience of ten years with nonimmune fetal ascites H. B. Ferreira, F. Taborda, A. S. Lacerda, S. Marta, R. Zulmira
Hospital Geral de Santo António, PortugalObjective: The aim of this study on fetal ascites was to review the frequency of etiologic factors and, to analyze the precision of prenatal ultrasound scan in defining the cause and prognostic factors. Methods: We conducted a retrospective study of 24 cases of nonimmune fetal ascites, from our hospital, over a 10-year period, from 1994 to 2004. Results: Ascites is an infrequent anomaly that is encountered during prenatal life. Its prevalence is difficult to establish because reported series are small and biased by the recruitment. Fetal ascites corresponds to the pres...
Objectives: To analyze the mid-term neurodevelopment outcome in children with isolated mild (≤ 12 mm) ventriculomegaly (VM) diagnosed in fetal life, using the Battelle Developmental Inventory Screening test (BDIST). Methods: Retrospective study in a tertiary care center. 86 cases of mild VM were identified, of which 68 were excluded due to additional cerebral anomalies (n = 40), extra-craneal anomalies (n = 3), chromosomal defects (n = 4), dysmorphic syndromes (n = 4), congenital infections (n = 2), termination of pregnancy (n = 9), stillbirth (n = 2) or incomplete follow-up (n = 4). Eighteen cases (range 1-8 years) of mild isolated VM were considered for full analysis. Six neurodevelopment domains (personal-social skills, adaptive behavior, fine and gross motor skills, communication and cognition) were assessed by the BDIST. For each domain, patients were classified as normal, borderline, moderate retardation This abstract has been shortlisted as a finalist for the Alfred Kratochwil 3D abstract award. The winner will be announced at the closing ceremony.
Objectives: To review 1 st trimester TVUS of patients with cervico-isthmic implantations & history of Cesarean deliveries to determine whether biometry can distinguish between placenta accreta, Cesarean scar pregnancy & other outcomes. Methods: Our database was reviewed from Oct 2006-Dec 2011 for patients with 1 st trimester US diagnoses of cervico-isthmic implantations & previous history of Cesarean deliveries. Biometry was performed based on location of the trophoblast on TVUS sagittal images of the uterus:
Oral communication abstracts proportion of prenatally diagnosed isolated facial clefts to 100%, without any influence on the number of terminations of pregnancy.
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