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Addiction has generally been characterized as a chronic relapsing condition. Several laboratory, preclinical, and clinical studies have provided evidence that craving and negative affect are strong predictors of the relapse process. These states, as well as the desire to avoid them, have been described as primary motives for substance use. A recently developed behavioral treatment, Mindfulness-Based Relapse Prevention (MBRP), was designed to target experiences of craving and negative affect and their roles in the relapse process. MBRP offers skills in cognitive behavioral relapse prevention integrated with mindfulness meditation. The mindfulness practices in MBRP are intended to increase discriminative awareness, with a specific focus on acceptance of uncomfortable states or challenging situations without reacting “automatically.” A recent efficacy trial found that those randomized to MBRP, as compared to those in a control group, demonstrated significantly lower rates of substance use and greater decreases in craving following treatment. Furthermore, individuals in MBRP did not report increased craving or substance use in response to negative affect. Importantly, areas of the brain that have been associated with craving, negative affect, and relapse have also been shown to be affected by mindfulness training. Drawing from the neuroimaging literature, we review several plausible mechanisms by which MBRP might be changing neural responses to the experiences of craving and negative affect, which subsequently may reduce risk for relapse. We hypothesize that MBRP may affect numerous brain systems and may reverse, repair, or compensate for the neuroadaptive changes associated with addiction and addictive behavior relapse.

We systematically reviewed empirical studies that investigated the use of cognitive-behavioral therapy (CBT) for premenstrual syndrome (PMS) or premenstrual dysphoric disorder (PMDD). Our multi-database search identified seven published empirical reports. Three were identified as randomized controlled trials (RCTs). The methods utilized to investigate therapeutic efficacy of CBT in these studies varied widely from case reports to RCTs with pharmacotherapy comparison groups. Initially we provide a brief overview of CBT and justifications for its potential use to treat PMS/PMDD. Next, we provide critical evaluations of the analyses used in each study focusing on the detection of intervention effects assessed by statistically significant time by group interactions. When possible we calculate effect sizes to elucidate the clinical significance of results. Our review revealed a dearth of evidence providing statistically significant CBT intervention effects. Issues such as overall time investment, latency to treatment effects, and complementary and combined therapies are considered. We present a theoretical argument for applying mindfulness- and acceptance-based CBT interventions to PMS/PMDD and suggest future research in this area. In conclusion, to produce the necessary evidence-base support for PMS/PMDD given the limited empirical evidence reported here, researchers are called on to produce methodologically rigorous investigations of psychosocial interventions for PMS/PMDD.

In the present study, the authors investigated the impact of exercise frequency, intensity, and volume along with exercise motives on quality of life (QOL) reports. The authors assessed exercise habits with the Godin Leisure Time Activity Scale and measured exercise motives with the Reasons for Exercise Inventory. The Quality of Life Inventory assessed satisfaction in 16 domains including health, work, and recreation. High-frequency exercisers reported significantly higher health, helping, and community-related QOL than those who exercised less frequently. The authors noted significantly higher health-related QOL in the heavy volume group compared with the other volume groups. Multiple regression tests revealed that activity intensity and exercise motives significantly predicted QOL reports. The strongest bivariate correlations with QOL existed for mild activity and exercising for fitness and health reasons. Thus, high-frequency activity of mild intensity that produces high kcal utilization and is performed to improve health and fitness has the strongest influence on QOL reports.

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Premenstrual symptomatology, stress, quality of life (QOL) and exercise frequency, volume, and intensity were assessed in 114 females (18-33 years). Based on premenstrual symptoms (PMS), women were divided into high and low PMS groups and compared on stress, QOL and exercise variables. Results revealed women with high PMS had significantly more stress and poorer QOL than women with low PMS (p <.05 for both comparisons). Groups did not significantly differ on any of the exercise variables. Further analyses were performed to determine if exercise variables impacted PMS symptoms, stress and QOL reports in the high PMS group. While exercise volume and intensity did not impact any of the variables assessed, women with high PMS who reported exercising "sometimes" had more stress than women who reported exercising "often" or "never". This nonlinear relationship suggests that women with the worst symptoms may respond by exercising, while women who exercise often or never do not associate exercise with their symptoms.

Alcohol use affects men and women differently, with women being more affected by the health effects of alcohol use (NIAAA, 2011). Yet, a dearth of information investigating the alcohol use in women exists (SAMSHA, 2011). In particular, one dispositional factor hypothesized to contribute to alcohol consumption in women is the menstrual cycle. However, only 13 empirical papers have considered the menstrual cycle as related to alcohol consumption in women. These studies fall out with somewhat mixed findings suggesting that the premenstrual week is associated with increased, decreased, or no change in alcohol consumption, likely due to methodological differences in menstrual cycle determination and measures of alcohol consumption. These methodological differences and possible other contributing factors are discussed here with recommendations for future research in this area. Understanding the contribution of the menstrual cycle to alcohol consumption is one step in addressing an important women’s health concern.

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