Adenoid cystic carcinoma of the paranasal sinuses is not a very common condition. It tends to arise from the maxillary antrum and can infiltrate into the surrounding tissue. They demonstrate perineural invasion into the maxillary and mandibular branches of trigeminal nerve.
Sarcoidosis is protean in its presenting characteristics. The most common pulmonary manifestations are hilar adenopathy and interstitial infiltrates. The alveolar filling pattern is noted less frequently. Here we present of a case of 53year-old woman who was diagnosed with alveolar sarcoidosis after an incidental finding on chest X-ray. CASE PRESENTATION: A 53-year-old woman was admitted to hospital for sepsis secondary to a urinary tract infection after presenting with fever, malaise and low abdominal pain. She had a 20-pack-year smoking history. On physical exam the chest was clear to auscultation. A routine chest X-ray (fig 1) showed an ill-defined density to the left hemithorax. She reported no cough, SOB, hemoptysis or other respiratory symptoms. CT chest showed a 2.9cm ground glass opacity in the superior segment of the left lower lobe (fig 2). Given the patient's smoking history, suspicion was high for malignancy. A CT guided transthoracic needle biopsy was done which showed non-caseating granulomata and no evidence of malignancy. Tissue smears were negative for bacteria, AFB and fungi, antigen tests for histoplasma and blastomyces were negative. ACE levels were elevated at 89U/L. A CT scan done 8 weeks following initial imaging showed complete resolution of the left lower lobe opacity (fig 3). PET scan done at that time showed no areas of increased uptake.
Objectives: To provide awareness to the pathologists and technologists all about the red cells parameters in cold antibodies concerned cases. Case Report Findings: A sixty seven-years-old male admitted in emergency department of our hospital, having clinical history of swelling and pain in both the lower limb and feet, on physical examination, provisionally diagnosed as a case of Cellulitis and deep vein thrombosis(DVT). Blood specimen was obtained for general hematological investigations. Full blood count (FBC) was performed on sysmex XP-100 hematological analyzer which showed invalid findings especially red cells indices which were not corresponding to the hemoglobin (Hb) concentration of the patient. Blood sample was repeated, to confirm invalid red cells indices which showed values as in the 1st blood specimen. Blood smears revealed aggregation of red cells. By warming the ethylenediamine tetra-acetic acid (EDTA) tube containing the blood specimen, in water bath at 37⁰C for one hour and repeated the FBC on hematological analyzer and found the corrected red cells indices. Conclusion: Basic knowledge of cold antibodies and warming the blood sample at 37⁰c for one hour helps the correct diagnosis.
Spindle cell carcinoma is a rare variant of squamous cell carcinoma. The most frequently affected site is larynx, however, it may infrequently occur in various organs; gingiva, tongue, upper aerodigestive tract including hypopharynx and nasal cavity, esophagus, skin and breast. Here is a case who presented in department of ENT with nasal complaints and was diagnosed with spindle cell carcinoma. Spindle cell carcinoma (SpCC) is a rare, high malignant variant of squamous cell carcinoma (SCC), which shows biphasic proliferation of conventional SCC component and malignant spindle shape cells with sarcomatous appearance.
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