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OBJECTIVE: To investigate whether time interval between meal and exercise alters the balance of substrate oxidation during an exercise bout. HYPOTHESIS: Exercise performed 3-h after meal induces a higher rate of lipid oxidation than when performed only 1-h after meal. RESEARCH METHODS AND PROCEDURES: Eight overweight and obese postmenopausal women (age: 57.472.4 y; BMI: 31.872.1 kg m À2 ; %FAT: 42.771.2%, mean7s.e.m.) performed two sessions of exercise training at an intensity corresponding to their ' crossover' point of substrate oxidation (COP ox ). One session was held 1 h after a standardized meal and the other, 3 h after an identical meal on another day. Substrate oxidation was evaluated by indirect calorimetry. Hormonal responses were investigated during exercise. RESULTS: Respiratory exchange ratio values were lower in the 3-h condition, showing higher lipid oxidation during exercise (average difference þ 38.972.7 mg min À1 ; Po0.001), while mean energy expenditure did not differ. Basal heart rate was reduced in the 3 h compared with the 1-h condition (7875 vs 8775 bpm; Po0.05). Glycemia, lactatemia and insulinemia were reduced when exercise was performed 3 h after meal (Po0.05). DISCUSSION: When exercise is performed 3 h after meal at an intensity corresponding to the COP ox , metabolic and hormonal responses are similar to those targeted during the submaximal exercise test performed at fast that we previously proposed to individualize exercise training in the obese.

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RésuméDes poules de trois génotypes NaNa (homozygotes « cou nu »), Nana + (hétérozygotes « cou nu ») et na + na + (plumage normal), écloses à partir des mêmes parents, ont