IntroductionThalassemia is an inherited blood disorder that requires lifelong adherence to a complicated and burdensome medical regimen which could potentially impact emotional functioning of patients.ObjectivesTo assess the prevalence of depression, anxiety and stress symptoms in adult patients with thalassemia.AimsTo explore possible demographic, medical, and psychosocial correlates of these symptoms.Methods117 patients (19-61 years old, M age = 37.2Plusmn;9.3; 63% female) took part in the study. Depression, anxiety stress scale (DASS) was used along with SF12 for health related quality of life and a questionnaire about sociodemographic characteristics. Statistical analysis was performed with SPSS 16.ResultsSevere depressive symptoms were found in 17 patients (15%), anxiety symptoms in 11(9.6%) and stress symptoms in 35(30.2%). Sex, age, education, marital status and income had no significant correlation with anxiety and stress. In depression there was a significant difference between single and married patients (x2=6.990 p< .05), with 58.8% of single patients suffering from more depressive symptoms. Higher stress symptoms had a significant correlation with symptoms severity (r=.452 p< .001) and the present socioeconomic situation in Greece (r=.632 p< .001).ConclusionsGiven these findings, regular screening for anxiety stress and depression symptoms could help to identify at-risk patients to provide them with appropriate psychological support with the goal of improving emotional health.
IntroductionSubjective well-being(SWB) is the scientific name for how people evaluate their lives, and since Thalassemia is an inherited blood disorder that requires lifelong adherence to a complicated and burdensome medical regimen, SWB could be easily underevaluated.ObjectivesTo measure the impact of SWB in adult patients with thalassemia.AimsTo explore possible demographic, physical, and psychosocial correlates in SWB.Methods117 patients(23-60 years old, Mean age=37.2±9.3; 73% females) took part in the study. Satisfaction with Life Scale(SWLS-Ed Diener) was used for SWB, along with SF12 for health related quality of life, Depression Anxiety Stress Scale (DASS), life orientation test(GrLOT-R) for dispositional optimism and a questionnaire about sociodemographic characteristics. Statistical analysis was performed with SPSS 21.Results16.8% of patients were substantially to extremely dissatisfied with their lives(SWLS=5-14). 16.4% were slightly below average(SWLS=15-19), 19.8% had an average score (SWLS=20-24) and the rest had a high(29.8%-25-29) and very high score(17.2%-30-35) respectively. There was a significant difference between males(M=20±7) and females(M=22.8±7.2)(t=-1.906-p=0.05). Multivariate analysis revealed that optimism(beta=-.403), stress(beta=-.415), spouse existence(beta=.155), and gender(beta=.228), explained 56.4% of the variance in SWB(adjusted R2=.564-p=0.026). Age, SF12, depression, anxiety and education had a Non Significant effect in the model.ConclusionsGiven these findings, almost half of thalassemia patients have average to low life satisfaction, something which implies that they are sometimes not functioning well because their unhappiness serves as a distraction. Talking to a psychologist or psychiatrist can often help the patient get moving in the right direction, although positive change will be up the person
IntroductionIron Chelation treatment (ICT) in beta-thalassemia major (beta-TM) patients undergoing blood transfusions can cause low satisfaction, low compliance, with possible negative consequences on treatment success, patients’ wellbeing, and costs.AimsThe purpose was to estimate the existing correlation between the Chelation therapy factor of the Specific Thalassaemia Quality of life instrument (STQOLI) and certain psychological assessments.MethodThe Chelation impact scale, of the Specific Thalassaemia Quality of life instrument (STQOLI), along with the Depression Anxiety Stress Scale (DASS) and the Satisfaction with Life Scale, were administered to 70 patients with thalassaemia Major on regular blood transfusion, registered with Thalassemia unit at General Hospital of Nikaia Greece.ResultsStatistical analysis revealed that Chelation impact in health related quality of life in patients with thalassaemia has a significant and negative correlation with depression (r=-.325 p< .001), anxiety (r=-.276 p< 0.05) and total DASS (r=-.308 p< .05) and a significant positive correlation with the psychosocial impact scale of the (STQOLI) (r=.463 p< .0001), the Satisfaction with Life Scale (r=.265 p< .05) and the Total scale of STQOLI (r=.784 p< .001).ConclusionThe better quality of life in the Chelation therapy factor a patient has the less anxious and depressed is feeling. Thalassaemia has a negative impact on emotional, social and well being in thalassaemia patients. Continuing support for better Chelation quality should be given to these patients. More understanding and support especially from health authorities, and the society is essential to enhance their quality of life.
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