O objetivo deste estudo foi revisar na literatura atual os métodos e variáveis do consumo máximo de oxigênio/potência aeróbia e aspectos relacionados com a capacidade aeróbia em pessoas com lesão da medula espinhal. Foi utilizada a busca através da base de dados Sciverse-com os seguintes termos: Spinal cord injury, Tetraplegia, Paraplegia cruzados com Physical endurance, Exercise tolerance, Peak oxygen consumption. Para inclusão no estudo os artigos deveriam obedecer os seguintes critérios a) avaliação da potencia aeróbia em pessoas com lesão da medula espinhal na fase crônica da lesão, b) resultados com tetraplégicos ou paraplégicos, c) interação dos itens anteriores com VO 2 máx (l/min ou ml/kg/min) e duração de esforço em cadeira de rodas, sendo publicados a partir do ano de 2000 até o presente momento da escrita do trabalho em 2012. Após cruzamentos de termos pré-selecionados, foram selecionados 26 artigos. A partir dos estudos revisados, observa-se uma grande variação de modelos, testes e maneiras de avaliar componentes fisiológicos relacionados aos sistemas cardiorrespiratórios e circulatórios. Esta gama de métodos parece estar relacionada à heterogeneidade da população/amostra e consequentemente, os resultados, por mais similares que sejam em alguns aspectos, apresentam valores discretos de proximidade, revelando uma necessidade de padronização para estes procedimentos nesta população. Com isto, é evidente a importância de estudos bem controlados e com nível tecnológico avançado para melhores prognósticos e acompanhamentos de pessoas com lesão da medula espinhal, seja para atividades esportivas, melhora de aspectos de riscos cardiovasculares ou para o cotidiano do dia a dia.
WBC count in the donor is analized, as well as the percentage of platelets lost. Collection efficiencie was determined as follows: total CD34+ cell count per apheresis / (whole blood volumen processed -anticoagulant volumen) x pre-CD34+ in percentage. Stadistical analysis was performed by using Student´s t test and P <0.05 was considered significant. Results: Two groups were analyzed: COBE ® Spectra (n = 59) and Spectra Optia ® (n = 56), whose populations are homogeneous. In the first group, 36 (61%) were males and 23 females (39%) vs 24 (43%) and 32 (57%) in the second. The median age was 48 vs 46.5 years (ranges 20-72, 21-73). The median height was 172 cm in the first group (range 151-193) versus 170 cm (range 153-192) in the second. The median weight of the donors was 78 kg (45-125) in the first group vs 73 kg (45-110) in the second group; the median weight of the recipients was 65 kg (39.8-100) vs 74 kg (48-108) in the first and second group respectively. Two donors required central venous catheter in the Optia group. No relevant adverse events were observed in any group during the apheresis procedures. The results of the pre and post apheresis variables analyzed in the donor, the product, as well as the characteristics of the procedure are shown in the table. Summary/Conclusion: In our experience, both apheresis systems are comparable for HPC collection, but the Optia ® system improves the quality of the product collected by reducing its hematocrit and therefore its contamination with red cells, which is important in the context of ABO incompatible allogeneic transplantation. We have found a significant better efficiency in the Optia ® group. We observed a similar apheresis time in both groups, slightly shorter with the Optia ® system, and it is necessary to process a smaller amount of blood volume with respect to the COBE ® Spectra.
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