Ring-closure reaction affording spiroisoxazolines and spiropyrazolines via a 1,3-dipolar cycloaddition between the title compounds, occurs with high regioselectivity.
Cycloaddition reactionsCycloaddition reactions O 0070 1,3-Dipolar Cycloadditions of Arylcarbonitrile Oxides and Diaryl Nitrilimines with Some 2-Arylmethylene-1,3-indanediones; Regiochemistry of the Reactions. -1,3-Dipolar cycloaddition reactions of the title arylmethyleneindanediones (I) with carbonitrile oxides and nitrilimines, generated in situ, result in the completely regioselective formation of spirocyclic adducts (III) (16 examples) and (V) (16 examples), respectively. -(BOUDRIGA, S.; ASKRI, M.; GHARBI, R.; RAMMAH*, M.; CIAMALA, K.; J.
The regio- and stereochemistry of spiro-adducts derived from [4+2] cycloaddition between the title compounds were deduced by 1H NMR data and the elucidated structure of the tetrasubstituted pyrroles obtained by acidic hydrolysis.
Isoquinoline derivativesIsoquinoline derivatives R 0420Reaction of 2-Benzoyl-1,2-dihydroisoquinoline-1-carbonitrile Tetrafluoroborate Salt with 2-Arylmethylene-1,3-indanediones. Regio-and Stereochemistry of the Reaction. Formation of Spiro Compounds. -The reaction of the Reissert-type isoquinolinium salt (I) with arylmethyleneindanediones (II) provides regio-and stereoselectively spiro-adducts (III), which give the more stable pyrrole compounds (IV) on acid hydrolysis. -(BOUDRIGA, S.; ASKRI, M.; RAMMAH*, M.; MONNIER-JOBE, K.; J.
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