Reaction of 2‐Benzoyl‐1,2‐dihydroisoquinoline‐1‐carbonitrile Tetrafluoroborate Salt with 2‐Arylmethylene‐1,3‐indanediones. Regio‐ and Stereochemistry of the Reaction. Formation of Spiro Compounds.

Abstract

Isoquinoline derivativesIsoquinoline derivatives R 0420Reaction of 2-Benzoyl-1,2-dihydroisoquinoline-1-carbonitrile Tetrafluoroborate Salt with 2-Arylmethylene-1,3-indanediones. Regio-and Stereochemistry of the Reaction. Formation of Spiro Compounds. -The reaction of the Reissert-type isoquinolinium salt (I) with arylmethyleneindanediones (II) provides regio-and stereoselectively spiro-adducts (III), which give the more stable pyrrole compounds (IV) on acid hydrolysis. -(BOUDRIGA, S.; ASKRI, M.; RAMMAH*, M.; MONNIER-JOBE, K.; J.