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Background: Dengue infection is the most important one in terms of morbidity and mortality. If the illness is not identified early in the course and not treated promptly when indicated, case fatality rate of DHF can go over 20% and that of DSS can be as high as 44%. Aims & Objective:To study the manifestations of seropositive dengue fever patients at tertiary care hospital Perambalur. Also to assess indicators associated with poor prognosis (DHF and DSS) for early recognition of complications. Materials and Methods:The present cross sectional study was conducted on 60 hospitalized adult patients during the period of one year. All Patients were assessed for clinical presentation and closely observed with investigations for the progression disease and complications. MAC capture ELISA for IgM, IgG capture ELISA and NS1 antigen by sandwich ELISA were used for investigation. Results: In the present study out of total 60 patients, more number of DF patients i.e. 33 (55%) were found followed by 19 (31.67%) of DHF cases and 8 (13.33%) of DSS cases. There were 61% secondary infections in our study. The common symptoms in the present study were 60 (100%) fever in all patients followed by 48 (80%) headache. Conclusion: Dengue fever infection was found more in younger age groups. The factors significantly associated with poor prognosis group (DHF/DSS) were anorexia, altered mentation, conjunctival injections, anaemia with Hb <10mg%, haemoconcentration with haematocrit > 40, thrombocytopenia and deranged liver enzymes SGOT. Cite this article as: Mavilla A, Dandekar RH. Screening and manifestations of seropositive dengue fever patients in Perambalur: A Hospital based study. Int J Med Sci Public Health 2014;3:745-748.

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Hepatitis B virus (HBV) infection is a major cause of morbidity and mortality worldwide. Hepatitis B is spread through contact with blood or body fluids of an infected person. Hepatitis B virus (HBV) is the major cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma. The likelihood of developing Chronic Hepatitis B is related to the age at which infection is acquired; the risk being lowest in adults and >90% in neonates whose mothers are hepatitis B e antigen positive. HBV is not directly cytopathic and liver injury appears to be mostly caused by repeated attempts of the host's immune responses to control the infection. After reviewing the various articles, the following protocols are best suited for the health care workers.

Background: Epilepsy is a chronic neurological disorder which affects about 0.5% to 1% of the population. The older antiepileptic drugs like carbamazepine and phenytoin are the mainstay of treatment of epilepsy. With the development of newer drugs for various type of epilepsy, the prescribing pattern for epilepsy has changed over the last decade. The objective of this study was to evaluate the prescription pattern of antiepileptic drugs in outpatient department of a tertiary care health care centre in Kerala and to assess how adherent they are to the available treatment guidelines of epilepsy.Methods: Data was collected from patients attending the outpatient department of Neurology in Government Medical College, Kozhikode for 2 months from January 2018 to February 2018. A total of 442 patients were enrolled in the study and data regarding the type of epilepsy, the antiepileptic drug prescribed, and the demographic profile were recorded and analysed.Results: Among the study participants, 237 were males (53.6%) and 205 females (46.2%). The study showed that among the 442 participants enrolled, the most common type of epilepsy was focal seizures (64.5%) and the most commonly prescribed drug was carbamazepine (28%), followed by levetiracetam (22%) and valproate (20%). Majority of the patients were treated with a single drug (79.2%).Conclusions: Newer drugs have been increasingly added to the list of antiepileptic drugs, but most of them serve as adjuvant to older ones and the important drugs used as monotherapy are still the older ones.