Hyperlipidemia is the major risk factor of arteriosclerosis, coronary heart diseases and death. Phenolic compounds have been shown to offer the protection against cardiovascular complications. In the present study, we studied the effect of semisynthetic phenolic compounds on the hyperlipidemic mice fed with high fat diet (cholesterol, cholic acid and peanut oil). Phenolic compounds were mixed with HFD and the dose of the test compounds were 1 0mg/kg for 6 weeks. After 6 weeks, the average body weight of lab diet, HFD, standard and test compounds were evaluated. Average body weight of test compound 1, test compound 2 and test compound 3 showed insignificant results (P>1) as compared to the standard drug (Atorvastatin in this study). The liver weight of mice increased (P>1) in all treatment groups relative to standard drug fed group. The plasma lipids such as triglyceride and LDL-cholesterol were found to be increased (P>1) in Test compound 1, test compound 2 , test compound 3 and HFD fed mice when compared to that of standard drug ( Atorvastatin) fed mice. But high-density lipoprotein (HDL) cholesterol increased in standard when compared to that of lab diet fed mice, HFD and test compounds. In conclusion, the supplementation of semi synthetic phenolic compounds may have a weak potential of hypolipidemic effect on mice fed high-fat diet.

This experiment was accompanied to examine the impact of yeast (Saccharomyces cerevisiae) supplemented with Selenium (se) or Zinc (zn) on the reproductive performance, estrogen and progesterone hormone in local Iraqi female goats. 17 mature does two - two and half years of old were used. The average of body weight (bw) was 37.5 ± 3kg. Animals were randomly divided in to three groups, Five animals were in the first group, six goats were in the second and third groups. All goat does were nursed on the same ration. The group1 was considered as a control group without processing (G1), the group 2 (G2) was administered with (Saccharomyces cerevisiae-selenium) with dose (0.03 g/kg/bw), the third group 3 (G3) were administered with (Saccharomyces cerevisiae -zinc with dose (0.2 g/kg/bw). (given orally for 45 days). The results showed that second and third groups were significantly increase (P≤0.05) in fertility and fertilization rate as compared with G1. G3 was significantly increase (P≤0.05) in the Prolificacy rate as compared with G1 and G2. G2 and G3 were significantly increase (P≤0.05) in the pregnancy rate as compared with G1. while G3 was significantly increase (P≤0.05) in the kidding rate as compared with G1 and G2. Estrogen hormone concentration level of the G2 showed a significant increase (P≤0.05) as compared with G1 and G3. While the progesterone hormone concentration level of the G3 showed a significant increase (P≤0.05) as compared with G1 and G2. From the results we concluded that organic form (yeast supplemented with selenium/zinc) could be credited to enhance the reproductive performance, overall health of kids after birth, progesterone levels and animal health.