Over a 6-year period, we studied 791 patients with multidrug-resistant typhoid fever, of whom 6 6 s individuals (84%) developed neuropsychiatric manifestations. These were: acute confusional state (73 %); myelitis ( 6 % ) ; cerebellitis ( I'%); parkinsonism (.r%); acute psychosis (0.6%); meningo-encephalitis (0.5%); encephalitis (0.25%); sensory motor polyneuropathy, polymyositis, acute schizophrenia and bizarre neurological syndromes (O.T 2% each). Severe parkinsonian rigidity and meningo-encephalitis are associated with significant morbidity but very low mortality (0.5%").
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