In this study, the NO-donating property of [Ru(BPG)Cl(NO)]Cl (BPG = N,N-bis(2-
pyridylmethyl)glycinato anion) via electrochemical activation was assessed. The synthesized BPG and
[Ru(BPG)Cl(NO)]Cl were characterized by UV-Vis and FT-IR spectroscopy. To determine if NO may
be released from the compound via one-electron reduction, cyclic voltammetric experiments in aqueous
and non-aqueous solutions were performed using a three-electrode cell consisting of glassy carbon
working electrode, Pt wire counter electrode and Ag/AgCl or Ag/Ag+ reference electrode. The
[Ru(BPG)Cl(NO)]Cl complex showed two one-electron reversible reductions in dimethylformamide,
which suggests decreased ability as NO donor. In aqueous solution at pH 2.0, [Ru(BPG)Cl(NO)]Cl
exhibited a one-electron irreversible reduction, which could be assigned to a Ru-NO centered reduction.
The irreversibility of the reduction could be due to NO labilization and suggests that
[Ru(BPG)Cl(NO)]Cl could be a potential NO donor in acidic aqueous medium.
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