: Cheap and clean energy demand is continuously increasing due to economic growth and industrialization. The energy sectors of several countries still employ fossil fuels for power production and there is a concern of associated emissions of greenhouse gases (GHG). On the other hand, environmental regulations are becoming more stringent, and resultant emissions need to be mitigated. Therefore, optimal energy policies considering economic resources and environmentally friendly pathways for electricity generation are essential. The objective of this paper is to develop a comprehensive model to optimize the power sector. For this purpose, a multi-period mixed integer programming (MPMIP) model was developed in a General Algebraic Modeling System (GAMS) to minimize the cost of electricity and reduce carbon dioxide (CO2) emissions. Various CO2 mitigation strategies such as fuel balancing and carbon capture and sequestration (CCS) were employed. The model was tested on a case study from Pakistan for a period of 13 years from 2018 to 2030. All types of power plants were considered that are available and to be installed from 2018 to 2030. Moreover, capacity expansion was also considered where needed. Fuel balancing was found to be the most suitable and promising option for CO2 mitigation as up to 40% CO2 mitigation can be achieved by the year 2030 starting from 4% in 2018 for all scenarios without increase in the cost of electricity (COE). CO2 mitigation higher than 40% by the year 2030 can also be realized but the number of new proposed power plants was much higher beyond this target, which resulted in increased COE. Implementation of carbon capture and sequestration (CCS) on new power plants also reduced the CO2 emissions considerably with an increase in COE of up to 15%.
Poliomyelitis (polio) remains a vital global public health challenge, particularly in countries where eradication efforts are ongoing. For almost three decades, polio programme and frontline workers in Pakistan have suffered human and financial losses due to complex political and bureaucratic management, local resistance to programme efforts, and the context of cross-border insurgency and insecurity.1 Many stakeholders in Pakistan continue to have low confidence in frontline workers and polio vaccination campaigns. In this environment, it is essential that vaccination programmes localise – by taking careful account of the local context, improving local ownership of the programmes, understanding and mitigating the issues at a grassroots level, and tailoring efforts to achieve polio eradication goals. This brief draws on evidence from academic and grey literature, data on polio vaccine uptake, consultations with partners working on polio eradication in Pakistan, and the authors’ own programme implementation experience in the country. The brief reviews the social, cultural, and contextual considerations relevant to increasing polio vaccine uptake amongst vulnerable groups in Pakistan’s tribal areas. It focuses on the current country context, in the aftermath of the 2018 merger of the former Federally Administered Tribal Areas (FATA) into Khyber Pakhtunkhwa province (KPK). This brief is part of a series authored by participants from the SSHAP Fellowship, and was written by Luqman Hakeem and Riaz Hussain from Cohort 2. Contributions were provided by response partners in Pakistan including health communication and delivery staff and local administrative authorities. This brief was reviewed by Muhammad Sufyan (University of Swabi) and Ilyas Sharif (Quaid-e-Azam College of Commerce, University of Peshawar). The brief was supported by Megan Schmidt-Sane and Santiago Ripoll at the Institute of Development Studies and is the responsibility of SSHAP.
Nanomedicine is used to cure cancer of many tissues such as ovarian cancer and multiple myeloma. With the help of nanotechnology, the probability of failure or rejection of a transplant, an organ is reduced. Nanomedicine is one of the latest and better fields which is used for the treatment of tumors. Some of the methods used to produce nanoparticles are discussed here. Many nanoparticles are used for the benefit of humans. The solvent is subsequently dispersed in a surfactant's aqueous media, resulting in the formation of a film in an instant colloidal suspension called solvent displacement. This method can be used to achieve a pharmacological payload. Supersaturation and precipitation are required for the assembly and stability of drug nanoparticles. Shear and cavitation forces are also used to produce nanoparticles. The milling media is generating shear forces on impact, resulting in nanoparticles, the principle of size reduction. Extrusion is also used to generate nanoparticles. Hydrophobic drugs are converted directly into nanoparticles. The capacity to build nanocores with a wide range of functionalities is another key advantage of the HAylation process (a method to make nanoparticles). Determine medication, metabolism and hepatotoxicity in these models in nanomedicine have the potential to have a significant influence in the field. Red blood cells (RBCs), for example, are sensitive to substantial external flow pressures, and their inherent formability can be used as a biomarker to identify a range of RBC diseases. It is concluded that different nanoparticles are made to treat different kinds of diseases and to make different therapies for cancer etc. Now a day’s nanotechnology is the method that uses nanoparticles to cure diseases and provide a significant treatment approach to humans.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.