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A series of four heterogemini surfactants have been synthesized: 2-decyl [dodecyl(dimethyl)ammonio]ethyl phosphate, decyl 2-(1-dodecylpyrrolidinio-1-yl)ethyl phosphate, decyl 2-(1-dodecylpiperidinio-1-yl)ethyl phosphate, and decyl 2-(1-dodecylmorpholinio-1-yl)ethyl phosphate. Antiprotozoal activity of prepared compounds against Acanthamoeba lugdunensis was investigated. Decyl 2-(1-dodecylpyrrolidinio-1-yl)ethyl phosphate exhibited the best trophocidal activity. The activities of heterogemini surfactants were compared with their aggregation properties. C

Synthesis, Aggregation Properties, and Antiprotozoal Activity of Heterocyclic Heterogemini Surfactants (I). -(LUKAC*, M.; TIMKO, L.; MRVA, M.; ONDRISKA, F.; KARLOVSKA, J.; VALENTOVA, J.; LACKO, I.; Heteroat. Chem.