The new RV analysis software allowed validation of the accuracy of 4D echo RV volume data compared with MRI.

No abstract

Background: We studied the role of 3D/4D ultrasound (US) for left atrial (LA) volume/function evaluation in patients with coronary artery disease (CAD) and congenital heart disease (CHD). Methods: 22 patients with CAD/CHD were studied with live 3D US and MRI. US images and MRI were obtained at the same visit. US images were acquired with a real time 3D US system (Philips 7500) and X3 matrix-array transducer with full volume sweeps in apical, 4 and 2 chamber views. MR images were acquired with a 1.5/3 T magnet with gradient cine-loop sequencing of the left atrium (LA). US images were analyzed with 4D view software (TomTec) using sagittal/4-chamber/coronal views. LA end diastolic and end systolic volumes (EDV, ESV) and stroke volume (SV) could be measured in all images. MR data were measured offline with Philips MRI software. Results: Regardless of LA shape and size, assessment with 3D US provided images of both the atrial body and appendage in all patients. 3D US results agreed closely with MRI. 3D US measured LA EDV 22.6 ml to 69.8ml, mean = 43.3 ml ± 16.3, while MRI measured LA EDV 20.3 ml to 64 ml, mean = 39.2ml ± 14.4 (r = 0.93). 3D US LA ESV was 14.2ml to 40.7ml, mean = 24.6 ml ± 8.6, while MRI LA ESV was 16.5ml to 41.3 ml, mean = 22.8 ml ± 9.4 (r = 0.95; p < 0.01). Conclusions: Despite the distance from the matrix array in 3D US, it can accurately quantify LA cavity and appendage volume and function.