secondary to breast cancer treated with percutaneous ablation and/ or cementoplasty or kyphoplasty. Data collected included patient demographics, performance status based on the Karnofsky Performance Scale (KPS), pain scores based on the visual acuity score, total follow up, lesion characteristics on imaging and as determined by the Spinal Instability Neoplastic Score (SINS), procedural technique, and any complications. Clinical success was determined by improvements in pain and performance status along with local tumor control. KPS and pain scores were recorded at baseline, one month, three months, and latest follow-up. Imaging at 3 and 6 months was reviewed to evaluate for local tumor control. Results: 44 spinal lesions and 7 pelvic lesions were treated, with lesions either lytic (n¼41), blastic (n¼5) or mixed sclerotic-lytic (n¼5) in nature. The mean SINS was 8.47 (SD2.25) (potentially unstable), with 19 lesions causing pathologic fractures. Radiofrequency ablation (RFA) was used to treat 40 lesions, cryoablation was used to treat one lesion. and kyphoplasty alone was used to treat 10 lesions Mean baseline KPS, at 1-month, 3-month, and latest follow up were 54 (SD 23.24), 65.8 (SD 24.5, p¼.04), 72 (SD 19.71, p<.01), and 63.15 (32.15, p¼.04), respectively. Mean pain scores at presentation, 1-month, 3-month, and at latest follow up were 7.75 (SD 1.84), 2.44 (SD 2.4), .45 (SD 1.15), and .93 (SD 1.62) respectively (p<.01 for all). There were no intra-operative or postoperative complications (mean follow up¼ 243 days). There was postoperative imaging for 26 (51%) lesions, which showed local tumor control rates of 100% (n¼10) at 3 months and 93.8% (n¼16) at 6 months. Conclusions: Percutaneous image-guided ablation for osseous metastases secondary to breast cancer was effective in relieving pain, improving performance status and in local tumor control in this population.
