Background Hepatitis B is one of the most common infectious diseases worldwide. Indonesia has moderate-high endemicity for hepatitis B infection. Perinatal transmission increases the risk for chronic hepatitis B. Infants from HBsAg-positive mothers should receive hepatitis B immunoglobulin (HBIG) and vaccination
Chatbot adalah sebuah program komputer yang dirancang untuk menstimulasikan sebuah percakapan atau komunikasi yang interaktif kepada pengguna (manusia) baik melalui tekt, suara ataupun visual. Chatbot telah banyak dimanfaatkan untuk tujuan praktis seperti bantuan online, layanan personal, atau akuisisi informasi. Seiring perkembangan yang pesat diperlukan respon yang cepat tidak terkecuali dalam kerja HelpDesk Kantor Pajak Pratama Binjai. Pada penelitian ini teknologi chatbot dirancang dengan menggunakan dialogflow yang terdiri dari agent, intent dan training phrase. Hasil uji coba melalui messenger menunjukkan sistem chatbot yang telah dirancang dapat bekerja dengan baik dan memberikan respon sesuai dengan kata kunci atau masukan yang terdapat pada training phrase dan respon yang sesuai.
Background This study evaluated thiamine levels in Indonesian children with congenital heart diseases before and after cardiopulmonary bypass and their relationship with clinical and surgical outcomes. Method A prospective, single center cross-sectional study was conducted to evaluate thiamine levels in 25 children undergoing congenital heart diseases surgery with cardiopulmonary bypass procedure. Thiamine levels were quantified using a high-performance liquid chromatography method. Result Preoperative thiamine deficiency was observed in one subject. Thiamine levels did not differ statistically between nutritional status and clinical outcomes categories. There were no significant changes in thiamine levels before and after cardiopulmonary bypass (median pre versus post (P25–75): 50 ng/mL (59.00–116.00) and 83.00 ng/mL (70.00–101.00), p = 0.84), although a significant reduction in thiamine levels were observed with longer cardiopulmonary bypass duration ( p = 0.017, R = −0.472). Conclusion Thiamine levels were not significantly impacted by cardiac surgery except in patients undergoing extremely long cardiopulmonary bypass duration. However, clinical outcome was not affected by thiamine levels.
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