For the first time in the medical literature, we detected sympathetic impairment during the active tilt test in chronic Chagas patients treated with benznidazole. This finding may be partially explained by benznidazole neurotoxicity.
OBJECTIVES:To describe the morphological features of atherosclerosis in the aortas of autopsied patients (ranging from young adults to the elderly), thus providing new tools for a more sensitive morphological evaluation.METHOD:We collected 141 aorta samples. We assessed the macroscopic degree of atherosclerosis, thickness of the intima and media, lipid and collagen depositions in the intima, and the infiltration of mast cells into the layers of the aorta. We correlated the findings with gender, age, race and cause of death.RESULTS:The degree of atherosclerosis was significantly higher in the elderly. The aorta was thicker in the elderly and in cases with a cardiovascular cause of death. The thickness of the intima was significantly greater in the elderly, in males and in cases with a cardiovascular cause of death. The lipid content in the intima of the aorta was significantly higher in Caucasians. Older people and men had a significantly higher number of mast cells.CONCLUSION:A macroscopic evaluation is a good indicator of the severity of atherosclerosis, but a more detailed analysis, namely evaluating the thickness of the layers of the aorta and the number of mast cells, may further elucidate the changes in the constituents of this vessel.
Objetivo: Conhecer o acolhimento na percepção dos usuários de uma estratégia de saúde da família. Métodos: O estudo é de natureza qualitativa, descritiva e exploratória. A coleta dos dados ocorreu por meio de entrevista estruturada. Como critérios de inclusão, os usuários necessitavam ser maiores de 18 anos, com registro na UBSF. A coleta de dados foi efetivada por meio de um roteiro prévio, desenvolvido pelos pesquisadores, com a finalidade de identificar a condição socioeconômica dos usuários. Resultados: Os entrevistados possuem em média uma renda mensal de um a dois salários mínimos, a maioria era do sexo feminino entre a faixa etária de 20 a 69 anos. Quanto à escolaridade constatamos que o maior percentual dos participantes declarou ensino médio completo. A análise temática possibilitou a construção de duas unidades: o atendimento com qualidade e o atendimento quanto à quantidade e ao tempo na Atenção Primária à Saúde. Conclusão: O usuário busca um ambiente de saúde resolutivo que organiza uma rica ação de retroalimentação, ou seja, uma via de mão dupla, na qual usuário e trabalhadores participam do processo de saúde.
Quantify steatosis, fibrosis, and focuses of extramedullary erythropoiesis (ER) in the liver and report it to the causes of death in the perinatal. Morphologic analysis of steatosis', percentage of fibrosis, and ER of 467 perinatal autopsies. Cases with hypoxia/perinatal anoxia and ascending infection showed higher percentage of fibrosis. The number of ER was significantly higher among premature infants and in cases with infection. Our results contribute to a better quality of perinatal care through clinical demonstration of which injuries are associated with them, what may help in early diagnosis of these alterations in children who survive.
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