Based on the data analysis of the 1000 hPa wind, SST and SSH anomalies, it is revealed that the atmospheric variations associated with Indian Ocean Dipole (IOD, or referred as Indian Ocean Zonal Dipole Mode, IOZDM) consist of a pair of anticyclones closely north and south of the equator with accompanying intense equatorial easterly anomalies, while the atmospheric variations related to El Niño/Southern Oscillation (ENSO) include a strong anticyclone in the southeastern tropical Indian Ocean (TIO) at higher latitudes with strong along‐shore wind anomalies near Java‐Sumatra coast. The different atmospheric forcing patterns lead to the fact that oceanic thermocline variations associated with IOD/IOZDM are more closely confined to the region north of 10°S, while ENSO‐induced thermocline variations are dominant south of 10°S.

The response of the Indian Ocean dipole (IOD) mode to global warming is investigated based on simulations from phase 5 of the Coupled Model Intercomparison Project (CMIP5). In response to increased greenhouse gases, an IOD-like warming pattern appears in the equatorial Indian Ocean, with reduced (enhanced) warming in the east (west), an easterly wind trend, and thermocline shoaling in the east. Despite a shoaling thermocline and strengthened thermocline feedback in the eastern equatorial Indian Ocean, the interannual variance of the IOD mode remains largely unchanged in sea surface temperature (SST) as atmospheric feedback and zonal wind variance weaken under global warming. The negative skewness in eastern Indian Ocean SST is reduced as a result of the shoaling thermocline. The change in interannual IOD variance exhibits some variability among models, and this intermodel variability is correlated with the change in thermocline feedback. The results herein illustrate that mean state changes modulate interannual modes, and suggest that recent changes in the IOD mode are likely due to natural variations.

Late generations of telomerase-null (TR(-/-)) mice exhibit progressive defects in highly proliferative tissues and organs and decreased fertility, ultimately leading to sterility. To determine effects of telomerase deficiency on germ cells, we investigated the cleavage and preimplantation development of embryos derived from both in vivo and in vitro fertilization of TR(-/-) or wild-type (TR(+/+)) sperm with either TR(-/-) or TR(+/+) oocytes. Consistently, fertilization of TR(-/-) oocytes with either TR(+/+) or TR(-/-) sperm, and TR(-/-) sperm with TR(+/+) oocytes, resulted in aberrant cleavage and development, in contrast to the normal cleavage and development of TR(+/+) oocytes fertilized by TR(+/+) sperm. Many (>50%) of the fertilized TR(-/-) eggs developed only one pronucleus, coincident with increased incidence of cytofragmentation, in contrast to the normal formation of two pronuclei and equal cleavage of wild-type embryos. These results suggest that both TR(-/-) sperm and oocytes contribute to defective fertilization and cleavage. We further found that a subset (7-9%) of telomeres was undetectable at the ends of some metaphase I chromosomes from TR(-/-) spermatocytes and oocytes, indicating that meiotic germ cells lacking telomerase ultimately resulted in telomere shortening and loss. Dysfunction of meiotic telomeres may contribute to aberrant fertilization of gametes and lead to abnormal cleavage of embryos, implying an important role of functional telomeres for germ cells undergoing fertilization and early cleavage development.

This study evaluates the simulation of the Indian Ocean Basin (IOB) mode and relevant physical processes in models from phase 5 of the Coupled Model Intercomparison Project (CMIP5). Historical runs from 20 CMIP5 models are available for the analysis. They reproduce the IOB mode and its close relationship to El Niño–Southern Oscillation (ENSO). Half of the models capture key IOB processes: a downwelling oceanic Rossby wave in the southern tropical Indian Ocean (TIO) precedes the IOB development in boreal fall and triggers an antisymmetric wind anomaly pattern across the equator in the following spring. The anomalous wind pattern induces a second warming in the north Indian Ocean (NIO) through summer and sustains anticyclonic wind anomalies in the northwest Pacific by radiating a warm tropospheric Kelvin wave. The second warming in the NIO is indicative of ocean–atmosphere interaction in the interior TIO. More than half of the models display a double peak in NIO warming, as observed following El Niño, while the rest show only one winter peak. The intermodel diversity in the characteristics of the IOB mode seems related to the thermocline adjustment in the south TIO to ENSO-induced wind variations. Almost all the models show multidecadal variations in IOB variance, possibly modulated by ENSO.

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The present study investigates interdecadal modulations of the El Niño-Southern

Objective According to routine activity theory and crime pattern theory, crime feeds on the legal routine activities of offenders and unguarded victims. Based on this assumption, the present study investigates whether daily mobility flows of the urban population help predict where individual thieves commit crimes. Methods Geocoded tracks of mobile phones are used to estimate the intensity of population mobility between pairs of 1616 communities in a large city in China. Using data on 3436 police-recorded thefts from the person, we apply discrete choice models to assess whether mobility flows help explain where offenders go to perpetrate crime. Results Accounting for the presence of crime generators and distance to the offender's home location, we find that the stronger a community is connected by population flows to where the offender lives, the larger its probability of being targeted. Conclusions The mobility flow measure is a useful addition to the estimated effects of distance and crime generators. It predicts the locations of thefts much better than the presence of crime generators does. However, it does not replace the role of distance, suggesting that offenders are more spatially restricted than others, or that even within their activity spaces they prefer to offend near their homes.

The Indian Ocean witnessed a weak positive Indian Ocean dipole (IOD) event from the boreal summer to autumn in 2015, while an extreme El Niño occurred over the tropical Pacific. This was different from the case in 1997/98, when an extreme El Niño and the strongest IOD took place simultaneously. The analysis here suggests that the unique sea surface temperature anomaly (SSTA) pattern of El Niño in 2015 might have contributed to the weak IOD that year. El Niño in 2015 had a complex SSTA pattern, with positive warming over the central and eastern tropical Pacific. Such a combination of the classic El Niño (also known as cold-tongue El Niño) and the recently identified central Pacific El Niño (also known as El Niño Modoki II) had opposite remote influences on the tropical Indian Ocean. The classic El Niño reduced the strength of the Walker circulation over the tropical Indian Ocean, but this was offset by El Niño Modoki II. This study points out that the IOD can be strongly modulated by combined El Niño types in some circumstances, as in 2015.