A catalytic defluorosilylation is disclosed that provides concise, modular synthetic entries to gem-difluoroallylsilanes from -trifluoromethylalkenes and silacarboxylic acids which are easy-to-prepare and stable silyl radical precursors. It is enabled by...
Radicals can be formed expeditiously through the direct irradiation of an electron donor‐acceptor (EDA) complex. Herein, we show a photocatalyst‐free strategy for gem‐difluoroalkenes synthesis realized by photo‐irradiation of the EDA complexes, which can be generated in situ between N‐alkylpyridinium salts and Hantzsch ester without any other additives. A wide variety of readily available alkylamines underwent deaminative defluoroalkylation to provide the corresponding gem‐difluoroalkenes. This reaction system exhibits high reactivity and good functional group tolerance and provides a practical and effective entry to a broad range of α‐alkyl‐substituted gem‐difluoroalkenes.
Herein, we disclose a new photoredox-catalyzed strategy to access gem-difluoroallylarenes from α-trifluoromethylalkenes with sterically hindered primary amines via C−N and C−F bond activation. This deaminative and defluorinative allylation is generally...
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